Nahrungsergänzungsmittel bestimmen
mit der Stimm-Frequenz-Analyse
Studien und Literatur zu in Nahrungsergänzungsmitteln enthaltenen Inhaltsstoffen
A
Acerola, Ackerschachtelhalm, Alfalfa, Alpha-Liponsäure, Aminosäuren, Amla, Apfelessig, Artischockenextrakt, Ashwagandha, Astaxanthin
B
C
D
E
F
G
H
K
L
M
N
O
P
Q
R
S
T
V
Vitamin B1 (Thiamin), Vitamin B2 (Riboflavin), Vitamin B3 (Niacin), Vitamin B6 (Pyridoxin), Vitamin B9 (Methylfolin), Vitamin B12 (Methylcobalamin), Vitamin C
W
Y
Z
Acerola
Düsman E et al, "In vivo antimutagenic
effects of the Barbados cherry fruit (Malpighia glabra Linnaeus)
in a chromosomal aberration assay", Genet Mol Res, Dezember 2016,
(In vivo antimutagene Wirkungen der Acerola-Kirsche (Malpighia
glabra Linnaeus) in einer
Chromosomenaberration-Analyse)
Chambial S et al, "Vitamin C in disease
prevention and cure: an overview", Indian J Clin Biochem, Oktober
2013, (Vitamin C in der Prävention und Behandlung von
Krankheiten: ein Überblick)
Horta RN et al, "Protective effects of acerola
juice on genotoxicity induced by iron in vivo", Genet Mol Biol,
März 2016, (In vivo Schutzwirkung von Acerola-Saft auf durch
Eisen verursachte Genotoxizität)
Paz M et al, "Brazilian fruit pulps as
functional foods and additives: evaluation of bioactive
compounds", Food Chem, April 2015, (Brasilianisches Fruchtfleisch
als funktionelle Lebensmittel und Additive: Die Bewertung
bioaktiver Stoffe)
Almeida IV et al, "Cytotoxic and mutagenic
effects of iodine-131 and radioprotection of acerola (Malpighia
glabra L.) and beta-carotene in vitro", Genet Mol Res, Dezember
2013
Ribeiro da Silva LM et al, "Quantification of
bioactive compounds in pulps and by-products of tropical fruits
from Brazil", Food Chem, Januar 2014, (Die Quantifizierung
bioaktiver Stoffe im Fruchtfleisch und in Nebenprodukten
tropischer Früchte aus Brasilien)
Costa A et al, "Clinical, biometric and
ultrasound assessment of the effects of daily use of a
nutraceutical composed of lycopene, acerola extract, grape seed
extract and Biomarine Complex in photoaged human skin", An Bras
Dermatol, Januar-Februar 2012
M.D. Norman W. Clein, "Acerola juiceThe richest
known source of Vitamin C: A clinical study in infants", The
Journal of Pediatrics, Februar 1956, (Acerola-Saft Die
gehaltvollste bekannte Vitamin-C- Quelle: Eine klinische Studie
an Kindern)
M. Mohammed, "Acerola (Malpighia emarginata
DC.), Postharvest Biology and Technology of Tropical and
Subtropical Fruits", 2011, (Acerola (Malpighia emarginata DC.),
Biologie und Technologie nach der Ernte von tropischen und
suptropischen Früchten)
T. Mezadria et al, "Antioxidant compounds and
antioxidant activity in acerola (Malpighia emarginata DC.) fruits
and derivatives", Journal of Food Composition and Analysis, Juni
2008, (Antioxidative Inhaltsstoffe und die antioxidative Wirkung
von Acerola-Früchten und entsprechenden Derivaten (Malpighia
emarginata DC.
Uchida E et al, "Absorption and excretion of
ascorbic acid alone and in acerola (Malpighia emarginata) juice:
comparison in healthy Japanese subjects", Biol Pharm Bull,
November 2011, (Die Absorption und Ausscheidung von
Ascorbinsäure per se und in Acerola-Fruchtsaft (Malpighia
emarginata): gesunde japanische Probanden im
Vergleich)
Mezadri T et al, "The acerola fruit:
composition, productive characteristics and economic importance",
Arch Latinoam Nutr, Juni 2006, (Die Acerola-Frucht:
Zusammensetzung, produktive Eigenschaften und wirtschaftliche
Bedeutung)
Gayle Engels, Josef Brinckmann, "Acerola
Malpighia emarginata, M. glabra", HerbalGram, 2014, (Acerola
Malpighia emarginata, M. Glabra)
Enstrom JE et al, "Vitamin C intake and
mortality among a sample of the United States population",
Epidemiology, Mai 1992, (Die Aufnahme von Vitamin C und die
Sterblichkeit anhand einer
US-Bevölkerungsstichprobe)
Luanda G. Marques et al, "Freeze-drying of
acerola (Malpighia glabra L.)", Chemical Engineering and
Processing: Process Intensification, Mai 2007, (Gefriertrocknung
der Acerola (Malpighia glabra L.))
Sandra Aparecida de Assis et al, "Acerola:
importance, culture conditions, production and biochemical
aspects", Cambridge University Press, März 2008, (Acerola:
Bedeutung, Zuchtbedingungen, Produktion und biochemische
Aspekte)
Lemne Delva et al, "Acerola (Malpighia
emarginata DC): Production, Postharvest Handling, Nutrition, and
Biological Activity", Food Reviews International, August 2012,
(Acerola (Malpighia emarginata DC): Produktion, Handhabe nach der
Ernte, Ernährung und Bioaktivität)
Ana Lcia A. Vendramini et al, "Phenolic
compounds in acerola fruit (Malpighia punicifolia, L.)", J Braz
Chem Soc, September-Oktober 2004, (Phenolische Verbindungen in
der Acerola-Frucht (Malpighia punicifolia, L.))
Frei B et al, Authors' perspective: What is the
optimum intake of vitamin C in humans? Crit Rev Food Sci Nutr,
2012
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activities of flavonoids: an overview, ScientificWorldJournal,
Dezember 2013
Verena Ahne et al, Gesundheit: Neue Studien zeigen den grossen Schwindel mit den teuren Vitaminpillen, Profil, Januar 2006
Ackerschachtelhalm
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Aminosäuren
Zu den semi-essenziellen Aminosäure
Zu den semi-essenziellen Aminosäuren
L-Leucin, Isoleucin und Valin
Kazuto T., et al. (2013), Branched-chain amino acids in liver diseases
Amla
Phyllanthus emblica bei Tropicos.org. In: IPCN Chromosome Reports. Missouri Botanical Garden, St. Louis.
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Apfelessig
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Ashwagandha
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Weitere Literatur
Steroidal lactones from Withania somnifera, an ancient plant for novel medicine - Molecules. 2009 Jul 3;14(7):2373-93
A Prospective, Randomized Double-Blind, Placebo-Controlled Study of Safety and Efficacy of a High-Concentration Full-Spectrum Extract of Ashwagandha Root in Reducing Stress and Anxiety in Adults - Indian J Psychol Med. 2012 Jul-Sep; 34(3): 255–262
Naturopathic care for anxiety: a randomized controlled trial ISRCTN78958974 - PLoS One. 2009 Aug 31;4(8):e6628. doi: 10.1371/journal.pone.0006628
Hypoglycemic, diuretic and hypocholesterolemic effect of winter cherry (Withania somnifera, Dunal) root - Indian J Exp Biol. 2000 Jun;38(6):607-9
Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Improving Sexual Function in Women: A Pilot Study - Biomed Res Int. 2015;2015:284154. doi: 10.1155/2015/284154. Epub 2015 Oct 4
Efficacy and Safety of Ashwagandha Root Extract in Subclinical Hypothyroid Patients: A Double-Blind, Randomized Placebo-Controlled Trial. - J Altern Complement Med. 2018 Mar;24(3):243-248. doi: 10.1089/acm.2017.0183
Role of ashwagandha methanolic extract in the regulation of thyroid profile in hypothyroidism modeled rats. - Mol Biol Rep. 2019 Aug;46(4):3637-3649. doi: 10.1007/s11033-019-04721-x
Ashwagandha - examine.com
Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study - Cureus,2019 Dec 25;11(12):e6466. doi: 10.7759/cureus.6466.
Studien-Übersicht Ashwagandha - KSM-66
Clinical evaluation of the pharmacological impact of ashwagandha root extract on sleep in healthy volunteers and insomnia patients: A double-blind, randomized, parallel-group, placebo-controlled study - J Ethnopharmacol. 2021 Jan 10;264:113276. doi: 10.1016/j.jep.2020.113276. Epub 2020 Aug 17.
Astaxanthin
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Quelle
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Betr. Silizium
Der Körper eines Erwachsenen kann etwa 1.4g Silizium speichern, hauptsächlich in Knochen und Bindegewebe.
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Baobab
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Bärlauch
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Beifuß
Hamacher-Brady, Anne, Henning A Stein, Simon Turschner, Ina Toegel, Rodrigo Mora, Nina Jennewein, Thomas Efferth, Roland Eils, and Nathan R Brady. 2010. Artesunate Activates Mitochondrial Apoptosis in Breast Cancer Cells via Iron-catalysed Lysosomal Reactive Oxygen Species Production. The Journal of Biological Chemistry 286 (8) (December 13): 6587–601. DOI: dx.doi.org/10.1074/jbc.M110.210047...
Division of Functional Genome Analysis... IPMC, MCA and MCAC samples. Panel (c), finally, presents a combination of the data with a colour-code added that indicated the tendency of malignancy of the re-spective tumour types: blue, non-malignant; red, highly malignant. figure ... Effect of Artesunate on pancreatic cancer cells, Helwan University, Cairo The paucity of curative therapies for pancreatic can-cer has translated into an overall 5-year survival rate of less than 5%, underscoring...
German Cancer Research Centre ...., Hofmann, A., Hub, B., Zentgraf, H., Lehmann, W.D. and Pereira, G. (2011). Phosphorylation-dependent regulation of the F-BAR protein Hof1 during cytokinesis. Genes & Dev., 25:875-888. Steinbrueck, L., Pereira, G. and Efferth, T. (2010). Effects of artesunate on cytokinesis and G2/M cell cycle progression of tumour cells and budding yeast. Cancer Genomics & Proteomics, 7:337-346. Caydasi, A.K., Kurtulmus, B., Orrico, M.I.L. , Hofmann, A. , Ibrahim, B. and Pereira, G. (2010). Elm1 kinase activates...
Malaria Drug Artesunate Activates Lysosomal Cell Death in Cancer Cells MALARIA DRUG ARTESUNATE ACTIVATES LYSOSOMAL CELL DEATH IN CANCER CELLS No. 36a | 11/07/2011 Heidelberg scientists have investigated cellular processes in killing breast cancer cells. enlarged view In cancer cells treated with arsenuate, mitochondria (green) as well as lysosomae (red) appear fragmented, accummulated around the nuclei. Untreated cancer cells, in contrast, appear to have a network of mitochondria and lyso-somae distributed evenly over the entire cell. | © dkfz.de Artemisinin – a substance...
Hamacher-Brady A., Stein H.A., Turschner S., Toegel I., Mora R., Jennewein N., Efferth T., Eils R. & Brady N.R. (2011). Artesunate activates mitochondrial apoptosis in breast cancer cells via iron-catalysed lyso-somal reactive oxygen species production. J Biol Chem., 285(8):6587-601 Hamacher-Brady A., Brady N.R., Logue S.E., Sayen M.R., Jinno M., Gottlieb R.A. & Gustafsson A.B...
Deutsches Krebsforschungszentrum JUNIOR RESEARCH GROUP SYSTEMS BIOLOGY OF CELL DEATH MECHANISMS DR. NATHAN BRADY 3D reconstruction of mitochondria (green), lysosomes (red) and nu-clei (grey). In response to artesunate, lysosomes cluster asymmetrically at the nucleus. Pro-death sig-naling from lysosomes induces mitochondrial fragmentation and convert mitochondria into inducers of cell death via cytochrome c release. Vergrößerte Ansicht 3D reconstruction of mitochondria (green), lysosomes (red) and nuclei (grey).
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Chlorella
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Trevors JT et al., "Cadmium transport, resistance, and toxicity in bacteria, algae, and fungi." Can J Micro-biol. 1986 Jun;32(6):447-64. (Cadmium Transport, Widerstand und Toxizität in Bakterien, Algen und Pil-zen.)
Nagafuchi S et al., "Effects of dietary nucleotides on serum antibody and splenic cytokine production in mice." Nutr Res. 1997;17:1163-1174. (Effekte von Nahrungsnukleotiden auf die Serum-Antikörper- und Milz-Zytokin-Produktion bei Mäusen.) (
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Maldonado JM et al., "Reversible inactivation by NADH and ADP on Chlorella fusca nitrate reductase." Biochem Biophys Res Commun. 1973 Mar 5;51(1):27-33. (Reversible Inaktivierung durch NADH und ADP der Chlorella fusca Nitrat-Reduktase.)
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Hernndez-Muoz R et al., "Adenosine partially prevents cirrhosis induced by carbon tetrachloride in rats." Hepatology. 1990 Aug;12(2):242-8. (Adenosin verhindert teilweise eine Leberzirrhose, die durch Tetrachlorkohlenstoff bei Ratten induziert wurde.)
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Agostoni C et al., "Characteristics of the new milks for infants: fatty acids, nucleotides, selenium." Acta Biomed Ateneo Parmense. 1997;68 Suppl 1:29-34. (Merkmale der neuen Milch für Kleinkinder: Fett-säuren, Nukleotide, Selen.)
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Carr HP et al., "Characterization of the cadmium-binding capacity of Chlorella vulgaris." Bull Environ Contam Toxicol. 1998 Mar;60(3):433-40. (Charakterisierung der Cadmium-Bindungskapazität von Chlo-rellavulgaris.)
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Saleh AM et al., "The nutritional quality of drum-dried algae produced in open door mass culture." Z Er-nahrungswiss. 1985 Dec;24(4):845-63. (Die ernährungsphysiologische Qualität von trommelgetrockne-ten Algen, die in einer Offenen-Tür-Massenkultur produziert wurden.)
Barashkov VA, Trubachev IN, Gitel`zon II. "Characteristics of the proteins of unicellular organisms as po-tential components of ecological life-support systems." Kosm Biol Aviakosm Med. 1979 May-Jun;13(3):75-80. (Eigenschaften der Proteine von einzelligen Organismen als potentielle Komponenten der kologischen Lebensgrundlagen.)
Cherng JY, Shih MF. "Improving glycogenesis in Streptozocin (STZ) diabetic mice after administration of green algae Chlorella." Life Sci. 2006 Feb 9;78(11):1181-6. (Verbesserung der Glykogenese in Strepto-zocin (STZ) diabetischen Mäusen nach Verabreichung der Grünalgen Chlorella.)
Rodrguez-Lpez M, Lpez-Quijada C. "Plasma-glucose and plasma-insulin in normal and alloxanized rats treated with Chlorella." Life Sci II. 1971 Jan 8;10(1):57-60. (Plasma-Glucose und Plasma-Insulin in nor-malen und all oxanizierten Ratten, die mit Chlorella behandelt wurden.)
Lee H et al., "Hypoglycemic action of chlorella" Taiwan Yi Xue Hui Za Zhi, 1977 Mar;76(3):272-6. (Blut-zuckersenkende Wirkung von Chlorella.)
Oomen AG et al., "Lead speciation in artificial human digestive fluid." Arch Environ Contam Toxicol. 2003 Jan;44(1):107-15. (Blei Speziation in künstlicher menschlicher Verdauungsflüssigkeit.)
Gunnison D, Alexander M. "Basis for the resistance of several algae to microbial decomposition." Appl Microbiol. 1975 Jun; 29(6):729-38. (Grundlage für den Widerstand mehrerer Algen gegen die mikro-bielle Zersetzung.)
Isaacs CE et al., "Inactivation of enveloped viruses in human bodily fluids by purified lipids." Ann N Y Acad Sci. 1994 Jun 6;724:457-64. (Die Inaktivierung von umhüllten Viren in menschlichen Körperflüs-sigkeiten, die von Lipiden gereinigt wurden.) (Studie als PDF)
Thormar H et al., "Inactivation of visna virus and other enveloped viruses by free fatty acids and mono-glycerides." Ann N Y Acad Sci. 1994 Jun 6;724:465-71. (Die Inaktivierung des Visnavirus und anderen umhüllten Viren durch freie Fettsäuren und Monoglyceride.)
Isaacs CE et al., "Antimicrobial activity of lipids added to human milk, infant formula, and bovine milk." J Nutr Biochem. 1995 Jul;6(7):362-366. (Die antimikrobielle Aktivität von Lipiden, die Muttermilch, Säug-lingsnahrung, Kuhmilch hinzugefügt wurden.)
Enig MG "Lauric oils as antimicrobial agents: theory of effect, scientific rationale, and dietary application as adjunct nutritional support for HIV-infected individuals." in Nutrients and Foods in AIDS, R.R. Watson, ed., CRC Press, Boca Raton, FL, pp. 81-97 (Laurinleals antimikrobielle Mittel: Theorie der Wirkung, der wissenschaftlichen Begründung und der Anwendung als Nahrungsergänzung für HIV-Infizierte.)
Petschow BW et al., "Susceptibility of Helicobacter pylori to bactericidal properties of medium-chain monoglycerides and free fatty acids." Antimicrob Agents Chemother. 1996 Feb;40(2):302-6. (Die Anfäl-ligkeit von Helicobacter pylori auf bakterizide Eigenschaften von mittelkettigen Monoglyceriden und freien Fettsäuren.)
Isaacs CE, Thormar H. "The role of milk-derived antimicrobial lipids as antiviral and antibacterial agents." Adv Exp Med Biol. 1991;310:159-65. (Die Rolle von antimikrobiellen Lipiden aus Milch als antivirale und antibakterielle Mittel.)
Crouch AA et al., "Effect of human milk and infant milk formulae on adherence of Giardia intestinalis." Trans R Soc Trop Med Hyg. 1991 Sep-Oct;85(5):617-9. (Die Wirkung von Muttermilch und Säuglings-nahrung auf die Anheftung von Giardiaintestinalis.) (Studie als PDF)
Bartol R et al., "Effect of olive oil on early and late events of colon carcinogenesis in rats: modulation of arachidonic acid metabolism and local prostaglandin E(2) synthesis." Gut. 2000 Feb;46(2):191-9. (Die Wirkung von Olivenöl auf frühe und späte Ereignisse der Kolonkarzinogenese bei Ratten: Modulation des Arachidonsäure-Stoffwechsels und lokaler ProstaglandinE (2)-Synthese.)
Ruiz-Gutierrez V et al., "Role of dietary oleic acid from two different sources on fatty acid composition of erythrocyte membrane and blood pressure in healthy subjects." J Nutr Biochem. 1997;8:689-695. (Die Rolle von Nahrungsölsäuren aus zwei verschiedenen Quellen auf die Fettsäurezusammensetzung der Erythrozytenmembran und den Blutdruck bei gesunden Probanden.)
Carluccio MA et al., "Oleic acid inhibits endothelial activation : A direct vascular antiatherogenic mech-anism of a nutritional component in the mediterranean diet." Arterioscler Thromb Vasc Biol. 1999 Feb;19(2):220-8. (Ölsäure hemmt die endotheliale Aktivierung: Ein direkter vasculärer antiatheroge-ner Mechanismus einer Nahrungskomponente in der Mittelmeer-Diät.)
Doktor Chlorella! Die Alge fürs Leben. Kompendium zur Mikroalge Chlorella von Dr. Frank Liebke
Citicholin
https://www.ncbi.nlm.nih.gov/pubmed/23387341
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782876/
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Coenzym Q10
1. Bhagavan HN, Chopra RK. “Plasma coenzyme Q10 response to oral ingestion of coenzyme Q10 formulations. Mitochondrion. 2007 Jun;7 Suppl:S78-88. (Coenzym Q10 Gehalt im Plasma nach oraler Verabreichung von Coenzym Q10 Rezepturen)
2. Shargorodsky M et al., “Effect of long-term treatment with antioxidants (vitamin C, vitamin E, coenzyme Q10 and selenium) on arterial compliance, humoral factors and inflammatory markers in patients with multiple cardiovascular risk factors. Nutr Metab (Lond). 2010 Jul 6;7:55. (Langzeiteffekte von Antioxidantien (Vitamin C, Vitamin E, Coenzym Q10 und Selenium) auf die Gefässe, humorale Faktoren und Entzündungsmarker bei Patienten mit kardiovaskulären Risikofaktoren)
3. Shults CW et al., “Effects of coenzyme Q10 in early Parkinson disease: evidence of slowing of the functional decline. Arch Neurol. 2002 Oct;59(10):1541-50. (Effekte von Coenzym Q10 bei Parkinson-Patienten im frühen Stadium)
4. Kooncumchoo P et al., “Coenzyme Q(10) provides neuroprotection in iron-induced apoptosis in dopaminergic neurons. J Mol Neurosci. 2006;28(2):125-41. (Coenzym Q10 schützt Nervenzellen)
5. Schmelzer C et al., “Functions of coenzyme Q10 in inflammation and gene expression. Biofactors. 2008;32(1-4):179-83. (Funktionen von Coenzym Q10 bei Entzündungen und der Genexpression)
6. Ravaglia G et al., “Effect of micronutrient status on natural killer cell immune function in healthy free-living subjects aged >/=90 y. Am J Clin Nutr. 2000 Feb;71(2):590-8. (Effekte von Mikronährstoffen auf den Status der natürlichen Killerzellen in gesunden Individuen über 90 Jahren)
7. Folkers K et al., “The activities of coenzyme Q10 and vitamin B6 for immune responses. Biochem Biophys Res Commun. 1993 May 28;193(1):88-92. (Die Aktivität von Coenzym Q10 und Vitamin B6 bei der Immunantwort)
8. Folkers K et al., “Biochemical deficiencies of coenzyme Q10 in HIV-infection and exploratory treatment. Biochem Biophys Res Commun. 1988 Jun 16;153(2):888-96. (Biochemischer Mangel an Q10 bei HIV-Infektionen)
9. DiMauro S. et al., “Exercise intolerance and the mitochondrial respiratory chain. Ital J Neurol Sci. 1999 Dec;20(6):387-93. (Umgebungsintoleranz und die mitochondriale Atmungskette)
10. Porter DA et al., “The effect of oral coenzyme Q10 on the exercise tolerance of middle-aged, untrained men. Int J Sports Med. 1995 Oct;16(7):421-7. (Die Effekte von oral eingenommenem Coenzym Q10 auf die Übungstoleranz von untrainierten Männern mittleren Alters)
11. Mizuno K et al., “Antifatigue effects of coenzyme Q10 during physical fatigue. Nutrition. 2008 Apr;24(4):293-9. (Anti-Erschöpfungs-Wirkung von Coenzym Q10 bei körperlicher Erschöpfung)
12. Barbiroli B et al., “Improved brain and muscle mitochondrial respiration with CoQ. An in vivo study by 31P-MR spectroscopy in patients with mitochondrial cytopathies. Biofactors. 1999;9(2-4):253-60. (Verbesserte mitochondriale Hirn und Muskel Leistung mit Coenzym Q10. Eine in vivo Studie bei Patienten mit mitochondrialer Zytopathie)
13. Folkers K, Simonsen R. “Two successful double-blind trials with coenzyme Q10 (vitamin Q10) on muscular dystrophies and neurogenic atrophies. Biochim Biophys Acta. 1995 May 24;1271(1):281-6. (Zwei erfolgreiche doppel-blind Versuche mit Coenzym Q10 bei Muskeldystrophien und neuronalen Atrophien)
14. Cordero MD et al., “Coenzyme Q10 distribution in blood is altered in patients with fibromyalgia. Clin Biochem. 2009 May;42(7-8):732-5. (Q10 Verteilung im Blut bei Patienten mit Fibromyalgie)
15. Lister RE. “An open, pilot study to evaluate the potential benefits of coenzyme Q10 combined with Ginkgo biloba extract in fibromyalgia syndrome. J Int Med Res. 2002 Mar-Apr;30(2):195-9. (Eine Pilot-Studie zur Evaluierung der potentiellen guten Eigenschaften von Coenzym Q10 mit Ginkgo biloba Extrakt bei Fibromyalgie)
16. Cooke M et al., “Effects of acute and 14-day coenzyme Q10 supplementation on exercise performance in both trained and untrained individuals. J Int Soc Sports Nutr. 2008 Mar 4;5:8. (Effekte von Coenzym Q10 auf die Übungsperformance von trainierten und untrainierten Individuen)
17. Echtay KS et al., “Uncoupling proteins 2 and 3 are highly active H(+) transporters and highly nucleotide sensitive when activated by coenzyme Q (ubiquinone). Proc Natl Acad Sci U S A. 2001 Feb 13;98(4):1416-21. (UCP 2 und UCP 3 sind hoch-aktive Wasserstoffionen-Transporter und hoch-Nukleotid-sensitiv, wenn sie von Coenzym Q10 aktiviert werden)
Cordyceps
Jones K: Cordyceps, Tonic Food of Ancient China. Sylvan Press, Seattle, 1997; 50 ff Halpern GM: Cordyceps, China`s Healing Mushroom. Avery Publishing Group, New York, 1999; 116 ff
Stamets P, Wu Yao CD: Mycomedicinals, An Informational Booklet on Medicinal Mushrooms. MycoMe-dia, Olympia WA, 1998; 46 ff
Zhu JS, Halpern GM, Jones K: The Scientific Rediscovery of an Ancient Chinese Herbal Medicine: Cordyceps sinensis.Part 1. Journal of Alternative and Complementary Medicine, 1998; 4(3):289-303 (Die wissenschaftliche Wiederentdeckung eines alten chinesischen Heilmittels: Cordyceps sinensis)
Zhu JS, Halpern GM, Jones K: The Scientific Rediscovery of a Precious Ancient Chinese Herbal Regimen: Cordyceps sinensis. Part 2. Journal of Alternative and Complementary Medicine, 1998; 4(4):429-457 (Die wissenschaftliche Wiederentdeckung eines wertvollen alten chinesischen Heilmittels: Cordyceps sinensis)
Seu-Mei Wang, Li Tjen Lee, Wan-Wan Lin, Chun-Min Chang: Effects of Water-Soluble Extract of Cordyceps sinensis on Steroidogenesis and Capsular Morphology of Lipid Droplets in Cultured Rat Adrenocortical Cells. Journal of Cellular Biochemistry, 1998; 69:483-489. (Wirkungen eines wasserlös-lichen Extrakts von Cordyceps sinensis auf die Steroidogenese und die Morphologie der Lipidtröpfchen bei kultivierten Rattenzellen aus der Nebennierenrinde)
Herbal Medicine: Biomolecular and Clinical Aspects. 2nd Edition, Chapter 5: Cordyceps as a Herbal Drug, Bao-qin Lin, Shao-ping Li, 2011 (Cordyceps als pflanzliches Heilmittel)
D-Galaktose
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Antranikian G. (2006): Angewandte Mikrobiologie. Springer-Verlag Berlin Heidelberg.
Aquer, C. et al. (2011): Galactose enhances oxidative metabolism and reveals mitochondrial dysfunction in human primary muscle cells. PLoS One. 2011; 6(12).https://www.ncbi.nlm.nih.gov/pubmed/22194845 , abgerufen am 02.12.2019.
Aue K. (2017) Störungen des Galactosestoffwechsels. Deutsche Apotheker Zeitung.https://www.deutsche-apotheker-zeitung.de/daz-az/2010/daz-25-2010/stoerungen-des-galactosestoffwechsels , abgerufen am 03.09.2017.
Austin, A.R. (2012): Effects of D-Galactose Treatment and Moderate Exercise on Spatial Memory in Rats. Dissertations, Western Michigan University.http://scholarworks.wmich.edu/cgi/viewcontent.cgi?article=1099&context=dissertations , abgerufen am 03.09.2017.
Bäßler, K. H. et al (1987): Grundbegriffe der Ernährungslehre. 4. Aufl. Springer-Verlag Berlin Heidelberg.
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Brahmachari, G. (2017): Neuroprotective Natural Products. Wiley-VCH West Bengal.
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Charrière, N. (2016): Cardiovascular responses to sugary drinks in humans: galactose presents milder cardiac effects than glucose or fructose. Eur J Nutr.https://www.ncbi.nlm.nih.gov/pubmed/27328681 , abgerufen am 03.09.2017.
Chogtu, B. et al. (2018): Evaluation of Acute and Chronic Effects of D-Galactose on Memory and Learning in Wistar Rats. Clin Psychopharmacol Neurosci. 2018; May 31, 16 (2), 153-160.https://pubmed.ncbi.nlm.nih.gov/29739128 , abgerufen am: 02.12.2019.
Clemens, R. A. (2016): Functionality of Sugars in Foods and Health. Comprehensive Reviews in Food Science and Food Safety 15(3): 433-470.http://onlinelibrary.wiley.com/doi/10.1111/1541-4337.12194/abstract , abgerufen am 03.09.2017.
Ercan, N. et al (1993): Effects of glucose, galactose, and lactose ingestion on the plasma glucose and insulin response in persons with non-insulin-dependent diabetes mellitus. Metabolism. 42(12):1560-7.https://www.researchgate.net/publication/14952061_Effects_of_glucose_galactose_and_lactose_ingestion_on_the_plasma_glucose_and_insulin_response_in_persons_with_non-insulin-dependent_diabetes_mellitus , abgerufen am 26.06.2018.
Gröber, U. (2014): Arzneimittel und Mikronährstoffe – Medikationsorientierte Supplementierung. 3. Aufl. Wissenschaftliche Verlagsgesellschaft mbH Stuttgart.
Gugliucci, A. (2017): Formation of Fructose-Mediated Advanced Glycation End Products and Their Roles in Metabolic and Inflammatory Diseases. Adv Nutr. 2017 Jan; 8(1): 54–62. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5227984 , abgerufen am: 25.11.2019.
Hill, T. (2009): Prüfungswissen Physikum. Georg Thieme Verlag Stuttgart
Kalichman, MW. et al. (1998): Reactive, degenerative, and proliferative Schwann cell responses in experimental galactose and human diabetic neuropathy. >Acta Neuropathol. 1998 Jan; 95(1): 47-56. https://www.ncbi.nlm.nih.gov/pubmed/9452821 , abgerufen am: 02.12.2019.
Khan, T. A. (2016): Controversies about sugars: results from systematic reviews and meta-analyses on obesity, cardiometabolic disease and diabetes. European Journal of Nutrition 55(2): 25–43. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5174149 , abgerufen am 03.09.2017.
Koenig, AM. et al. (2017): Effects of the Insulin Sensitizer Metformin in Alzheimer Disease: Pilot Data From a Randomized Placebo-controlled Crossover Study. Alzheimer Dis Assoc Disord. 2017 Apr-Jun;31(2):107-113. https://www.ncbi.nlm.nih.gov/pubmed/28538088 , abgerufen am: 02.12.2019.
Kosterlitz, H. et al. (1933): Untersuchungen über die Verwertung der Galaktose in physiologischen und pathologischen Zuständen. Zeitschrift für die gesamte experimentelle Medizin 1933, 87(1):411-415.< https://link.springer.com/article/10.1007/BF02610499 , abgerufen am: 29.11.2019.
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Li, C.; Shi, S. (2019): Neuroprotective Effect of Huperzine A on d-Galactose-Induced Hearing Dysfunction. Ear Nose Throat J. 2019 Sep 25.; https://www.ncbi.nlm.nih.gov/pubmed/31554431 , abgerufen am: 02.12.2019.
Lian, W. et al. (2017): Multi-Protection of DL0410 in Ameliorating Cognitive Defects in D-Galactose Induced Aging Mice. Front Aging Neurosci. 2017 Dec 8;9:409. https://www.ncbi.nlm.nih.gov/pubmed/29276489 , abgerufen am: 02.12.2019.
Macdermid, P.W. et al. (2012): A comparative analysis between the effects of galactose and glucose supplementation on endurance performance. Int J Sport Nutr Exerc Metab. 22(1):24-30. https://www.ncbi.nlm.nih.gov/pubmed/22248497 , abgerufen am 03.09.2017.
Max Rubner-Institut (Hrsg.) (2014): Ernährungsphysiologische Bewertung von Milch und Milchprodukten und ihren Inhaltsstoffen. https://www.bmel.de/SharedDocs/Downloads/Ernaehrung/Gesundheit/Milch-und-Milchprodukte.pdf?__blob=publicationFile , abgerufen am 03.09.2017.
Mosetter, K. und Ruetter, W. (2007): Insulin und Insulinresistenz im Gehirn. Schweiz. Zschr. GanzheitsMedizin 19(3):138–141. https://de.scribd.com/document/205621155/Insulin-Und-Insulinresistenz-Im-Gehirn-Mosetter-Reutter-2007-Schw , abgerufen am 26.06.2018.
Murata, M. et al. (2002): Selective pericyte degeneration in the retinal capillaries of galactose-fed dogs results from apoptosis linked to aldose reductase-catalyzed galactitol accumulation. J Diabetes Complications. 2002 Sep-Oct; 16(5): 363-70. https://www.ncbi.nlm.nih.gov/pubmed/12200082 , abgerufen am: 02.12.2019.
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O'Hara, J. P. et al. (2014): The effect of pre-exercise galactose and glucose ingestion on high-intensity endurance cycling. J Strength Cond Res. 28(8):2145-53. https://www.ncbi.nlm.nih.gov/pubmed/24476772 , abgerufen am 03.09.2017.
Ott, A. (1999): Diabetes mellitus and the risk of dementia: The Rotterdam Study. Neurology. 53(9):1937-42. https://www.ncbi.nlm.nih.gov/pubmed/10599761 , abgerufen am 03.09.2017.
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Reutter, W. (keine Angaben): Störungen im Zuckerstoffwechsel und dadurch bedingte gesundheitliche Schäden. Wie können wir ihnen begegnen? Produktinformation zu Progalin. http://www.progal.info/index.php?pg=25 , abgerufen am 12.04.2017.
Roser, M. et al. (2009): Metabolism of galactose in the brain and liver of rats and its conversion into glutamate and other amino acids. J Neural Transm (Vienna) 116 (2): 131–139. http://www.ncbi.nlm.nih.gov/pubmed/19089315 , abgerufen am: 27.11.2019.
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D-Mannose
1) Kranjcec B et al. World J Urol 2014; 32: 79–84
2) Porru D et al. J Clin Urol 2014; 7: 208–13
3) https://www.awmf.org/uploads/tx_szleitlinien/043-044l_S3_Harnwegsinfektionen_2017-05.pdf
4) Xiaohua Jiang, X.; et al.: Antiadhesion Therapy for Urinary Tract Infections - A Balanced PK/PD Profile Proved To Be Key for Success. J. Med. Chem. 2012; 55(10): 4700 – 4713.
5) Di Martino, P.; et al.: Reduction of Escherichia coli adherence to uroepithelial
D-Ribose
[1] Pliml et al (1992)
Studienart: randomisiert kontrollierte Studie
Teilnehmer: 20 Männer mit koronarer Herzkrankheit
Fragestellung: Verbessert D-Ribose die Herzleistung bei stabiler koronarer Herzkrankheit?
Mögliche Interessenkonflikte: keine angegeben
Effects of ribose on exercise-induced ischaemia in stable coronary artery disease. Lancet 1992;340:507-510 (Zusammenfassung der Studie)
[2] Omran et al (2003)
Studienart: randomisiert kontrollierte Studie
Teilnehmende: 15 Personen mit Herzinsuffizienz infolge stabiler Herz-Kreislauf-Erkrankung
Fragestellung: Welchen Effekt hat D-Ribose auf Herzfunktion und Lebensqualität?
Mögliche Interessenkonflikte: keine angegeben
D-Ribose improves diastolic function and quality of life in congestive heart failure patients: a prospective feasibility study. Eur J Heart Fail. 2003 Oct;5(5):615-9 (Zusammenfassung der Studie)
[3] Shecterle (2012)
Studienart: narrative Übersichtsarbeit
Alterations in Myocardial Cellular Energy and Diastolic Function, a Potential Role for D-Ribose. INTECH Open Access Publisher, 2012 (Übersichtsarbeit in voller Länge)
Weitere wissenschaftliche Quellen
[4] Shecterle u.a. (2010)
The patented uses of D-ribose in cardiovascular diseases. Recent Pat Cardiovasc Drug Discov. 2010 Jun;5(2):138-42 (Zusammenfassung der Arbeit)
[5] Gonzalez u.a. (2009)
Ribose treatment reduced the infarct size and improved heart function after myocardial infarction in rats. Cell Physiol Biochem. 2009; 24(3-4): 211-8 (Zusammenfassung der Tierstudie)
[6] Zimmer u.a. (1989)
Myocardial infarction in rats: effects of metabolic and pharmacologic interventions. Basic Res Cardiol. 1989 May-Jun; 84(3):332-43 (Zusammenfassung der Tierstudie)
[7] Zimmer & Gerlach (1978)
Stimulation of myocardial adenine nucleotide biosynthesis by pentoses and penitols. Pflugers Arch 1978;376:223-227 (Zusammenfassung der Tierstudie)
[8] Pasque u.a. (1982)
Ribose-enhanced myocardial recovery following ischemia in the isolated working rat heart. J Thorac Cardio-vasc Surg 1982;83:390-398 (Zusammenfassung der Tierstudie)
[9] St. Cyr u.a. (1989)
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Echinacea
European Medicines Agency (EMA): Echinaceae angustifoliae radix. Online: https://www.ema.europa.eu/en/medicines/herbal/echinaceae-angustifoliae-radix (Abgerufen 05/2020)
European Medicines Agency (EMA): Echinaceae pallidae radix. Online: https://www.ema.europa.eu/en/medicines/herbal/echinaceae-pallidae-radix (Abgerufen 05/2020)
European Medicines Agency (EMA): Echinaceae purpureae radix. Online: https://www.ema.europa.eu/en/medicines/herbal/echinaceae-purpureae-radix (Abgerufen 05/2020)
European Medicines Agency (EMA): Echinaceae purpureae herba. Online: https://www.ema.europa.eu/en/medicines/herbal/echinaceae-purpureae-herba (Abgerufen 05/2020)
National Center for Complementary and Integrative Health (NIH): Echinacea. Online: https://www.nccih.nih.gov/health/echinacea (Abgerufen 05/2020)
Eichenrinde
Pellegrini, L., et al., Supplementary management of functional, temporary alcoholic hepatic damage with Robuvit® (French oak wood extract). Minerva Gastroenterol Dietol. 2016 Sep;62(3), S. 245 – 52.
Eierschalenmembranpulver
Eskiyurt N, Saridogan M, Senel K, Günaydin R, Erdal A, et al. (2019) Efficacy and Safety of Natural Eggshell Membrane (NEM®) in Patients with Grade 2/3 Knee Osteoarthritis: A Multi-Center, Randomized, Double-blind, PlaceboControlled, Single-crossover Clinical Study. J Arthritis 8: 285. Quelle
Danesch U, Seybold M, Rittinghausen R, Treibel W, Bitterlich N (2014) NEM® Brand Eggshell Membrane Effective in the Treatment of Pain Associated with Knee and Hip Osteoarthritis: Results from a Six Center, Open Label German Clinical Study. J Arthritis 3: 136. doi:10.4172/2167-7921.1000136. Quelle
Ruff KJ, Morrison D, Duncan SA, Back M, Aydogan C, Theodosakis J. Beneficial effects of natural eggshell membrane versus placebo in exercise-induced joint pain, stiffness, and cartilage turnover in healthy, postmenopausal women. Clin Interv Aging. 2018;13:285-295. Published 2018 Feb 19. doi:10.2147/CIA.S153782. Quelle
Ruff KJ, DeVore DP, Leu MD, Robinson MA. Eggshell membrane: a possible new natural therapeutic for joint and connective tissue disorders. Results from two open-label human clinical studies. Clin Interv Aging. 2009;4:235-240. doi:10.2147/cia.s5797. Quelle
Hewlings S, Kalman D, and Schneider L V. A Randomized, Double-Blind, Placebo-Controlled, Prospective Clinical Trial Evaluating Water-Soluble Chicken Eggshell Membrane for Improvement in Joint Health in Adults with Knee Osteoarthritis. Journal of Medicinal Food. 22; 9: 875-884. Published September 2019. doi:10.1089/jmf.2019.0068. Quelle
Bhandari A. Natural Eggshell Membrane Improves Post-Exercise Pain and Stiffness. Implications for exercise compliance in sedentary patients. Natural Medicine Journal. 2018:10(10). Quelle
Yoo J, Park K, Yoo Y, Kim J, Yang H, Shin Y. Effects of Egg Shell Membrane Hydrolysates on Anti-Inflammatory, Anti-Wrinkle, Anti-Microbial Activity and Moisture-Protection. Korean J Food Sci Anim Resour. 2014;34(1):26-32. doi:10.5851/kosfa.2014.34.1.26. Quelle
Park, Ki-Moon & Yoo, Jin-Hee & Shin, Young-Jae. (2012). Effects of Egg Shell Membrane Hydrolysates on Skin Whitening, Wound Healing, and UV-Protection. Korean Journal for Food Science of Animal Resources. 32. 10.5851/kosfa.2012.32.3.308. Quelle
Kalman, DS, Hewlings, S. The effect of oral hydrolyzed eggshell membrane on the appearance of hair, skin, and nails in healthy middle-aged adults: A randomized double-blind placebo-controlled clinical trial. J Cosmet Dermatol. 2020; 19: 1463– 1472. https://doi.org/10.1111/jocd.13275. Quelle
Sakai S, Hien VTT, Tuyen LD, Duc HA, Masuda Y, Yamamoto S. Effects of Eggshell Kalzium Supplementation on Bone Mass in Postmenopausal Vietnamese Women. J Nutr Sci Vitaminol (Tokyo). 2017;63(2):120-124. doi:10.3177/jnsv.63.120. Quelle
Wedekind, Karen & Coverdale, Josie & Hampton, Thomas & Atwell, Cindy & Sorbet, Roy & Lunnemann, Jenea & Harrell, Robert & Greiner, Laura & Keith, Nancy & Evans, Joseph & Zhao, Junmei & Knight, Chris. (2015). Efficacy of an equine joint supplement, and the synergistic effect of its active ingredients (chelated trace minerals and natural eggshell membrane), as demonstrated in equine, swine, and an osteoarthritis rat model. Open Access Animal Physiology. 7. 7-13. 10.2147/OAAP.S75022. Quelle
Ruff KJ, Kopp KJ, Von Behrens P, Lux M, Mahn M, Back M. Effectiveness of NEM® brand eggshell membrane in the treatment of suboptimal joint function in dogs: a multicenter, randomized, double-blind, placebo-controlled study. Vet Med (Auckl). 2016;7:113-121. Published 2016 Aug 18. doi:10.2147/VMRR.S101842. Quelle
Ruff K J, Endres J R, Clewell A E, Szabo J R, Schauss A G. Safety evaluation of a natural eggshell membrane-derived product. Food and Chemical Toxicology. 2012;50(3-4):604-611. doi:10.1016/j.fct.2011.12.036. Quelle
Vitalstoff Journal. Eierschalenmembran: Eine Pilotstudie über die Wirksamkeit beim Menschen. Quelle
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Herrero-Beaumont G, Ivorra JA, Del Carmen Trabado M, et al. Glucosamine sulfate in the treatment of knee osteoarthritis symptoms: a randomized, double-blind, placebo-controlled study using acetaminophen as a side comparator. Arthritis Rheum. 2007;56(2):555-567. doi:10.1002/art.22371. Quelle
Geba GP, Weaver AL, Polis AB, Dixon ME, Schnitzer TJ, for the VACT Group. Efficacy of Rofecoxib, Celecoxib, and Acetaminophen in Osteoarthritis of the Knee: A Randomized Trial. JAMA. 2002;287(1):64–71. doi:10.1001/jama.287.1.64. Quelle
Towheed T, Maxwell L, Judd M, Catton M, Hochberg MC, Wells GA. Acetaminophen for osteoarthritis. Cochrane Database of Systematic Reviews 2006, Issue 1. Art. No.: CD004257. DOI: 10.1002/14651858.CD004257.pub2. Quelle
Hippisley-Cox Julia, Coupland Carol. Risk of myocardial infarction in patients taking cyclo-oxygenase-2 inhibitors or conventional non-steroidal anti-inflammatory drugs: population based nested case-control analysis BMJ 2005; 330 :1366. Quelle
Hawkey C J. Nonsteroidal anti-inflammatory drug gastropathy. gastroenterology. special reports and reviews. 2000;119(2):521-535. doi:10.1053/gast.2000.9561. Quelle
Enzyme
Jeremy M. Berg, John L. Tymoczko, Lubert Stryer: Biochemie. 5. Auflage. Spektrum Akademischer Verlag, Heidelberg – Berlin 2003, ISBN 3-8274-1303-6.
David Fell: Understanding the Control of Metabolism. Portland Press Ltd, London 1997, 2003, ISBN 1-85578-047-X.
Alfred Schellenberger (Hrsg.): Enzymkatalyse. Einführung in die Chemie, Biochemie und Technologie der Enzyme. Gustav Fischer Verlag, Jena 1989. ISBN 3-540-18942-4
Donald Voet, Judith G. Voet: Biochemistry. 3. Auflage. John Wiley & Sons Inc., London 2004, ISBN 0-471-39223-5.
Erbsenprotein
1. Cermak NM, Res PT, de Groot LC, Saris WH, van Loon LJ. Protein supplementation augments the adaptive response of skeletal muscle to resistance-type exercise training: a meta-analysis. Am J Clin Nutr. 2012 Dec;96(6):1454-64. Quelle
2. Finger D, Goltz FR, Umpierre D, Meyer E, Rosa LH, Schneider CD. Effects of protein supplementation in older adults undergoing resistance training: a systematic review and meta-analysis. Sports Med. 2015 Feb;45(2):245-55. Quelle
3. Brad Jon Schoenfeld, Alan Albert Aragon, James W Krieger.The effect of protein timing on muscle strength and hypertrophy: a meta-analysis. Journal of the International Society of Sports Nutrition. 2013; volume 10, Article number: 53. Quelle
4. Luisa Low. Put down the protein shake:
variety of protein better for health.
1 May 2019. University of Sydney. Quelle
Flohsamenschalen
Pal, S. and Radavelli-Bagatini, S. (2012), Effects of psyllium on metabolic syndrome risk factors.Obesity Reviews, 13: 10341047. doi: 10.1111/j.1467-789X.2012.01020.x, (Die Effekte von Flohsamen auf Risikofaktoren des Metabolischen Syndroms)
Weitere Quellen und Studien finden Sie hier: Darmreinigung aus wissenschaftlicher Sicht
Gerstengras
1. Yu YM, Chang WC, Chang CT, Hsieh CL, Tsai CE. Effects of young barley leaf extract and antioxidative vitamins on LDL oxidation and free radical scavenging activities in type 2 diabetes. Diabetes Metab. 2002 Apr;28(2):107-14. PMID: 11976562 Titel anhand dieser Pubmed-ID in Citavi-Projekt übernehmen. Quelle
2. Venugopal, Shonima & Iyer, Uma. (2010).
Management of diabetic dyslipidemia with subatmospheric
dehydrated barley grass powder. International Journal of Green
Pharmacy. 4. 10.4103/0973-8258.74134. Quelle
3. Jeong HJ, Lam Y, de Lumen BO. Barley lunasin suppresses ras-induced colony formation and inhibits core histone acetylation in mammalian cells. J Agric Food Chem. 2002 Oct 9;50(21):5903-8. doi: 10.1021/jf0256945 Titel anhand dieser DOI in Citavi-Projekt übernehmen. PMID: 12358457 Titel anhand dieser Pubmed-ID in Citavi-Projekt übernehmen. Quelle
4. Kanauchi O, Suga T, Tochihara M, Hibi T, Naganuma M, Homma T, Asakura H, Nakano H, Takahama K, Fujiyama Y, Andoh A, Shimoyama T, Hida N, Haruma K, Koga H, Mitsuyama K, Sata M, Fukuda M, Kojima A, Bamba T. Treatment of ulcerative colitis by feeding with germinated barley foodstuff: first report of a multicenter open control trial. J Gastroenterol. 2002 Nov;37 Suppl 14:67-72. doi: 10.1007/BF03326417 Titel anhand dieser DOI in Citavi-Projekt übernehmen. PMID: 12572869 Titel anhand dieser Pubmed-ID in Citavi-Projekt übernehmen. Quelle
5. Berkemeyer S. Acid-base balance and weight gain: are there crucial links via protein and organic acids in understanding obesity? Med Hypotheses. 2009 Sep;73(3):347-56. doi: 10.1016/j.mehy.2008.09.059. Epub 2009 May 1. PMID: 19410381. Quelle
6. Bioverfügbarkeit und Metabolismus von beta-Carotin und ausgewählten Vitamin E-Verbindungen, Anne Kathrin Kleine, 2007 Quelle
Granatapfel
Lansky EP, Newman RA: Punica granatum (pomegranate) and its potential for prevention and treatment of inflammation and cancer. J Ethnopharmacol 109:177-206, 2007.PMID:17157465
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Auerbach L, Rakus J, Bauer C et al.: Pomegranate seed oil in women with menopausal symptoms: a prospective randomized, placebo-controlled, double-blinded trial. Menopause 19:426-432, 2012. DOI:10.1097/gme.0b013e3182345b2f
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Ismail T, Sestili P, Akhtar S: Pomegranate peel and fruit extracts: A review of potential anti-inflammatory and anti-infective effects. J Ethnopharmacol 143:397-405, 2012. DOI:10.1016/j.jep.2012.07.004
Albrecht M, Jiang W, Kumi-Diaka J et al.: Pomegranate extracts potently suppress proliferation, xenograft growth, and invasion of human prostate cancer cells. J Med Food 7:274-283, 2004. PMID:15383219
Malik A, Afaq F, Sarfaraz S et al.: Pomegranate fruit juice for chemoprevention and chemotherapy of prostate cancer. Proc Natl Acad Sci USA 102(41):14813-14818, 2005. PMID:16192356
Adams LS, Zhang Y, Seeram NP et al.: Pomegranate ellagitannin-derived compounds exhibit antiproliferative and antiaromatase activity in breast cancer cells in vitro. Cancer Prev Res (Phila) 3:108-113, 2010. DOI:10.1158/1940-6207.CAPR-08-0225
Seeram NP, Adams LS, Henning SM et al.: In vitro antiproliferative, apoptotic and antioxidant activities of punicalagin, ellagic acid and a total pomegranate tannin extract are enhanced in combination with other polyphenols as found in pomegranate juice. J Nutr Biochem 16:360-367, 2005. PMID:15936648
Zavery B, Appleton L, Sandiford K et al.: Complementary and alternative medicine use amongst oncology patients attending a large cancer centre in England. Progress in Palliative Care 18: 89-93, 2010. DOI:10.1179/096992610X12624290276548
McLay JS, Stewart D, George J et al.: Complementary and alternative medicines use by Scottish women with breast cancer. What, why and the potential for drug interactions? Eur J Clin Pharmacol 68:811-819, 2012. DOI:10.1007/s00228-011-1181-6
Medicines and Healthcare products Regulatory Agency (MHRA). Prohibited or restricted herbal ingredients (2011). Available at: http://www.mhra.gov.uk/Howweregulate/Medicines/Herbalmedicinesregulation/Prohibitedorrestrictedherbalingredients/index.htm . Accessed 4th October 2012.
Adhami VM, Khan N, Mukhtar H: Cancer chemoprevention by pomegranate: laboratory and clinical evidence. Nutr Cancer 61:811-815, 2009. DOI:10.1080/01635580903285064
Pantuck AJ, Zomorodian N, Belldegrun AS: Phase-II Study of pomegranate juice for men with prostate cancer and increasing PSA. Curr Urol Rep 7:7. 2006. PMID:16480662
Carducci MA, Paller CJ, Wozniak P et al.: A phase II study of pomegranate extract for men with rising prostate-specific antigen following primary therapy. J Clin Oncol 29: 2011 (suppl 7; 11).
Sturgeon SR, Ronnenberg AG: Pomegranate and breast cancer: possible mechanisms of prevention. Nutr Rev 68:122-128, 2010.
DOI:10.1111/j.1753-4887.2009.00268.x
Banerjee S, Kambhampati S, Haque I, Banerjee SK: Pomegranate sensitizes Tamoxifen action in ER-a positive breast cancer cells. J Cell Commun Signal 5:317-324, 2011. DOI:10.1111/j.1753-4887.2009.00268.x
Sánchez-Lamar A, Fonseca G, Fuentes JL et al.: Assessment of the genotoxic risk of Punica granatum L. (Punicaceae) whole fruit extracts. J Ethnopharmacol 115:416-422, 2008. PMID:18036756
Jarvis S, Li C, Bogle RG: Possible interaction between pomegranate juice and warfarin. Emerg Med J 27:74-75, 2010. DOI:10.1136/emj.2007.055855
Komperda KE: Potential interaction between
pomegranate juice and warfarin. Pharmacotherapy. 2009
29(8):1002-1006, 2009. DOI:10.1136/emj.2007.055855
Sorokin AV, Duncan B, Panetta R, Thompson PD: Rhabdomyolysis associated with pomegranate juice consumption. Am J Cardiol 98:705-706, 2006. PMID:16923466
Vlachojannis C, Zimmermann BF, Chrubasik-Hausmann S: Efficacy and safety of pomegranate medicinal products for cancer. Evid Based Complement Alternat Med 2015:258598, 2015. DOI:10.1155/2015/258598
Freedland SJ, Carducci M, Kroeger N et al.: A double-blind, randomized, neoadjuvant study of the tissue effects of POMx pills in men with prostate cancer before radical prostatectomy. Cancer Prev Res (Phila) 6:1120-1127, 2013. DOI:10.1158/1940-6207.CAPR-12-0423
Stenner-Liewen F, Liewen H, Cathomas R et al.: Daily pomegranate intake has no impact on PSA levels in patients with advanced prostate cancer - results of a phase IIb randomized controlled trial. J Cancer 4:597-605, 2013. DOI:10.7150/jca.7123
Paller CJ, Ye X, Wozniak PJ et al.: A randomized phase II study of pomegranate extract for men with rising PSA following initial therapy for localized prostate cancer. Prostate Cancer Prostatic Dis 16:50-55, 2013. DOI:10.1038/pcan.2012.20
Sahebkar A, Gurban C, Serban A et al.: Effects of supplementation with pomegranate juice on plasma C-reactive protein concentrations: A systematic review and meta-analysis of randomized controlled trials. Phytomedicine 23:1095-1102, 2016. DOI:10.1016/j.phymed.2015.12.008
Turrini E, Ferruzzi L, Fimognari C. Potential Effects of Pomegranate Polyphenols in Cancer Prevention and Therapy. Oxid Med Cell Longev 2015:938475, 2015. DOI:10.1155/2015/938475
Pantuck AJ, Pettaway CA, Dreicer R et al.: A randomized, double-blind, placebo-controlled study of the effects of pomegranate extract on rising PSA levels in men following primary therapy for prostate cancer. Prostate Cancer Prostatic Dis 18:242-248, 2015. DOI:10.1038/pcan.2015.32
Nuñez-Sánchez MA, Dávalos A, González-Sarrías A et al.: MicroRNAs expression in normal and malignant colon tissues as biomarkers of colorectal cancer and in response to pomegranate extracts consumption: Critical issues to discern between modulatory effects and potential artefacts. Mol Nutr Food Res 59:1973-1986, 2015. DOI:10.1002/mnfr.201500357
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Zarfeshany A, Asgary S and Javanmard SH. Potent health effects of pomegranate. Adv Biomed Res 3: 100, 2014. DOI:10.4103/2277-9175.129371
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Abdlekawy KS, Donia AM, Elbarbry F. Effects of Grapefruit and Pomegranate Juices on the Pharmacokinetic Properties of Dapoxetine and Midazolam in Healthy Subjects. Eur J Drug Metab Pharmacokinet 42:397-405, 2017. DOI:10.1007/s13318-016-0352-3
Griffonia
Van Praag, H.M. and Westenberg, H.G.M., The treatment of depressions with L–5–hydroxytryptophan. In: H.M. Van Praag and J. M[endlewicz (Kds.). Treatment of Depression with Monoamine Precursors. 1980.
Carnevale G, Di Viestia V, Zavatti M, Zanoli P. Anxiolytic–like effect of Griffonia simplicifolia Baill. seed extract in rats. Phytomedicine 2011; 18: 848–851
Grünlippmuschel
Studien zur Grünlippmuschel bei Arthrose
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Bui L.M., Bierer T.L. Influence of green lipped mussels (Perna canaliculus) in alleviating signs of arthritis in dogs. Vet Ther, 2003, 4(4), 397-407. Pubmed
Cayzer J., Hedderley D., Gray S. A randomised, double-blinded, placebo-controlled study on the efficacy of a unique extract of green-lipped mussel (Perna canaliculus) in horses with chronic fetlock lameness attributed to osteoarthritis. Equine Vet J, 2011. Pubmed
Cobb C.S., Ernst E. Systematic review of a marine nutriceutical supplement in clinical tri-als for arthritis: the effectiveness of the New Zealand green-lipped mussel Perna cana-liculus. Clin Rheumatol, 2006, 25(3), 275-84. Pubmed
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Halpern G.M. Anti-inflammatory effects of a stabilized lipid extract of Perna canaliculus (Lyprinol). Allerg Immunol (Paris), 2000, 32(7), 272-8. Pubmed
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Martina V, et al., (2001), Administration of glutathione in patients with type 2 diabetes melli-tus increases the platelet constitutive nitric oxide synthase activity and reduces PAI-1.
5-HTP
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Serotonin im Darm, Depression heute, 2014
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Hagebuttenpulver
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Hanf-Öl (CBD)
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L-Arginin
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Liebstöckel
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Ling Shi/Reishi
1. Lin Z. Ganoderma (Lingzhi) in Traditional Chinese Medicine and Chinese Culture. Adv Exp Med Biol. 2019;1181:1-13. doi: 10.1007/978-981-13-9867-4_1. Review. PubMed PMID: 31677138. (https://www.ncbi.nlm.nih.gov/pubmed/31677138
2. Wang SY, Hsu ML, Hsu HC, Tzeng CH, Lee SS, Shiao MS, Ho CK. The anti-tumor effect of Ganoderma lucidum is mediated by cytokines released from activated macrophages and T lymphocytes. Int J Cancer. 1997 Mar 17;70(6):699-705. doi: 10.1002/(sici)1097-0215(19970317)70:6<699::aid-ijc12>3.0.co;2-5. PMID: 9096652. (https://pubmed.ncbi.nlm.nih.gov/9096652/
3. Lull C, Wichers HJ, Savelkoul HF. Antiinflammatory and immunomodulating properties of fungal metabolites. Mediators Inflamm. 2005 Jun 9;2005(2):63-80. doi: 10.1155/MI.2005.63. PMID: 16030389; PMCID: PMC1160565. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1160565/
4. Nkodo A. A Systematic Review of in-vivo Studies on Dietary Mushroom Supplementation for Cognitive Impairment (P14-021-19). Curr Dev Nutr. 2019 Jun 13;3(Suppl 1):nzz052.P14-021-19. doi: 10.1093/cdn/nzz052.P14-021-19. PMCID: PMC6574952. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6574952/
5. Matsuzaki H, Shimizu Y, Iwata N, Kamiuchi S, Suzuki F, Iizuka H, Hibino Y, Okazaki M. Antidepressant-like effects of a water-soluble extract from the culture medium of Ganoderma lucidum mycelia in rats. BMC Complement Altern Med. 2013 Dec 26;13:370. doi: 10.1186/1472-6882-13-370. PMID: 24369991; PMCID: PMC3879659. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879659/
6. Chu, Qing-Ping & Wang, Li-En & Cui, Xiang-Yu & Fu, Hong-Zheng & Lin, Zhi-Bin & Lin, Shu-Qian & Zhang, Yong-He.(2007). Extract of Ganoderma lucidum potentiates pentobarbital-induced sleep via a GABAergic mechanism. Pharmacology, biochemistry, and behavior. 86. 693-8. 10.1016/j.pbb.2007.02.015. (https://www.researchgate.net/publication/6423256_Extract_of_Ganoderma_lucidum_potentiates_pentobarbital-induced_sleep_via_a_GABAergic_mechanism
7. Qiu, Zhiwei & Zhong, Dandan & Yang, Baoxue. (2019). Preventive and Therapeutic Effect of Ganoderma (Lingzhi) on Liver Injury. 10.1007/978-981-32-9421-9_9. (https://www.researchgate.net/publication/337577750_Preventive_and_Therapeutic_Effect_of_Ganoderma_Lingzhi_on_Liver_Injury
8. Xiao, Chun & Wu, Qing-Ping & Cai, Wen & Tan, Jian-Bin & Yang, Xiao-Bing & Zhang, Ju-Mei. (2012). Hypoglycemic effects of Ganoderma lucidum polysaccharides in type 2 diabetic mice. Archives of pharmacal research. 35. 1793-801. 10.1007/s12272-012-1012-z. (https://www.researchgate.net/publication/233384962_Hypoglycemic_effects_of_Ganoderma_lucidum_polysaccharides_in_type_2_diabetic_mice
9. Chen, Wei-qiang & Luo, Shao-hong & Ll, Hong-zhi & Yang, Hong. (2005). [Effects of ganoderma lucidum polysaccharides on serum lipids and lipoperoxidation in experimental hyperlipidemic rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 30. 1358-60. ( https://www.researchgate.net/publication/7444738_Effects_of_ganoderma_lucidum_polysaccharides_on_serum_lipids_and_lipoperoxidation_in_experimental_hyperlipidemic_rats)
11. Keine sichere Webseite
12. Wachtel-Galor S, Yuen J, Buswell JA, et al. Ganoderma lucidum (Lingzhi or Reishi): A Medicinal Mushroom. In: Benzie IFF, Wachtel-Galor S, editors. Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition. Boca Raton (FL): CRC Press/Taylor & Francis; 2011. Chapter 9. (https://www.ncbi.nlm.nih.gov/books/NBK92757/)
13. Henao SLD, Urrego SA, Cano AM, Higuita EA. Randomized Clinical Trial for the Evaluation of Immune Modulation by Yogurt Enriched with ß-Glucans from Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), in Children from Medellin, Colombia. Int J Med Mushrooms. 2018;20(8):705-716. doi: 10.1615/IntJMedMushrooms.2018026986. PMID: 30317947. (https://pubmed.ncbi.nlm.nih.gov/30317947/)
14. Chiu HF, Fu HY, Lu YY, Han YC, Shen YC, Venkatakrishnan K, Golovinskaia O, Wang CK. Triterpenoids and polysaccharide peptides-enriched Ganoderma lucidum: a randomized, double-blind placebo-controlled crossover study of its antioxidation and hepatoprotective efficacy in healthy volunteers. Pharm Biol. 2017 Dec;55(1):1041-1046. doi: 10.1080/13880209.2017.1288750. PMID: 28183232; PMCID: PMC6130508. (https://pubmed.ncbi.nlm.nih.gov/28183232/)
15. Shevelev OB, Seryapina AA, Zavjalov EL, Gerlinskaya LA, Goryachkovskaya TN, Slynko NM, Kuibida LV, Peltek SE, Markel AL, Moshkin MP. Hypotensive and neurometabolic effects of intragastric Reishi (Ganoderma lucidum) administration in hypertensive ISIAH rat strain. Phytomedicine. 2018 Mar 1;41:1-6. doi: 10.1016/j.phymed.2018.01.013. Epub 2018 Jan 31. PMID: 29519314. (https://pubmed.ncbi.nlm.nih.gov/29519314/)
16. Wang GH, Li X, Cao WH, Li J, Wang LH. A retrospective study of Ganoderma Lucidum Spore Powder for patients with epilepsy. Medicine (Baltimore). 2018 Jun;97(23):e10941. doi: 10.1097/MD.0000000000010941. PMID: 29879039; PMCID: PMC5999473. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999473/)
17. Wang J, Cao B, Zhao H, Feng J. Emerging Roles of Ganoderma Lucidum in Anti-Aging. Aging Dis. 2017 Dec 1;8(6):691-707. doi: 10.14336/AD.2017.0410. PMID: 29344411; PMCID: PMC5758346. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758346/)
18. Al Alawi AM, Majoni SW, Falhammar H. Magnesium and Human Health: Perspectives and Research Directions. Int J Endocrinol. 2018 Apr 16;2018:9041694. doi: 10.1155/2018/9041694. PMID: 29849626; PMCID: PMC5926493. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926493/)
19. Sohretoglu D, Huang S. Ganoderma lucidum Polysaccharides as An Anti-cancer Agent. Anticancer Agents Med Chem. 2018;18(5):667-674. doi: 10.2174/1871520617666171113121246. PMID: 29141563; PMCID: PMC6624854. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624854/)
20. Sliva D. Ganoderma lucidum (Reishi) in cancer treatment. Integr Cancer Ther. 2003 Dec;2(4):358-64. doi: 10.1177/1534735403259066. PMID: 14713328. (https://pubmed.ncbi.nlm.nih.gov/14713328/)
21. Tao J, Feng KY. Experimental and clinical studies on inhibitory effect of ganoderma lucidum on platelet aggregation. J Tongji Med Univ. 1990;10(4):240-3. doi: 10.1007/BF02887938. PMID: 2098581. (https://pubmed.ncbi.nlm.nih.gov/2098581/)
22. Lin X, Ruiz Beguerie J, Sze DM, Chan GC. Ganoderma lucidum (Reishi mushroom) for cancer treatment. Cochrane Database Syst Rev. 2016 Apr 5;4(4):CD007731. doi: 10.1002/14651858.CD007731.pub3. PMID: 27045603; PMCID: PMC6353236. (https://pubmed.ncbi.nlm.nih.gov/27045603/)
Bai, J. H., J. Xu, J. Zhao, and R. Zhang. “Ganoderma Lucidum Polysaccharide Enzymatic Hydrolysate Suppresses the Growth of Human Colon Cancer Cells Via Inducing Apoptosis.” Cell Transplant 29 (Jan-Dec 2020): 963689720931435. https://dx.doi.org/10.1177/0963689720931435
Chen, M., D. Xiao, W. Liu, Y. Song, B. Zou, L. Li, P. Li, Y. Cai, D. Liu, Q. Liao, and Z. Xie. “ Intake of Ganoderma Lucidum Polysaccharides Reverses the Disturbed Gut Microbiota and Metabolism in Type 2 Diabetic Rats. ” Int J Biol Macromol 155 (Jul 15 2020): 890-902. https://dx.doi.org/10.1016/j.ijbiomac.2019.11.047
Gonzalez, A., V. Atienza, A. Montoro, and J. M. Soriano. “ Use of Ganoderma Lucidum (Ganodermataceae, Basidiomycota) as Radioprotector.” Nutrients 12, no. 4 (Apr 19 2020). https://dx.doi.org/10.3390/nu12041143
Huang, Y., G. Wei, X. Peng, G. Hu, H. Su, J. Liu, X. Chen, and M. Qiu. “ Triterpenoids from Functional Mushroom Ganoderma Resinaceum and the Novel Role of Resinacein S in Enhancing the Activity of Brown/Beige Adipocytes.” Food Res Int 136 (Oct 2020): 109303. https://dx.doi.org/10.1016/j.foodres.2020.109303
Jiao, C., Y. Xie, H. Yun, H. Liang, C. He, A. Jiang, Q. Wu, and B. B. Yang. “ The Effect of Ganoderma Lucidum Spore Oil in Early Skin Wound Healing: Interactions of Skin Microbiota and Inflammation.” Aging (Albany NY) 12, no. 14 (Jul 21 2020): 14125-40. https://dx.doi.org/10.18632/aging.103412
Lai, P., X. Cao, Q. Xu, Y. Liu, R. Li, J. Zhang, and M. Zhang. “ Ganoderma Lucidum Spore Ethanol Extract Attenuates Atherosclerosis by Regulating Lipid Metabolism Via Upregulation of Liver X Receptor Alpha.” Pharm Biol 58, no. 1 (Dec 2020): 760-70. https://dx.doi.org/10.1080/13880209.2020.1798471
Li, D., L. Gao, M. Li, Y. Luo, Y. Xie, T. Luo, L. Su, T. Yong, S. Chen, C. Jiao, J. Su, and S. Huang. “ Polysaccharide from Spore of Ganoderma Lucidum Ameliorates Paclitaxel-Induced Intestinal Barrier Injury: Apoptosis Inhibition by Reversing Microtubule Polymerization. Biomed Pharmacother 130 (Aug 5 2020): 110539. https://dx.doi.org/10.1016/j.biopha.2020.110539
Liu, X., Y. Xu, Y. Li, Y. Pan, Z. Sun, S. Zhao, and Y. Hou. “ Ganoderma Lucidum Fruiting Body Extracts Inhibit Colorectal Cancer by Inducing Apoptosis, Autophagy, and G0/G1 Phase Cell Cycle Arrest in Vitro and in Vivo.” Am J Transl Res 12, no. 6 (2020): 2675-84. https://www.ncbi.nlm.nih.gov/pubmed/32655799
Nascimento, C. P., D. A. Luz, C. C. S. da Silva, C. M. R. Malcher, L. M. P. Fernandes, H. S. Dalla Santa, A. R. Q. Gomes, M. C. Monteiro, Chma Ribeiro, E. A. Fontes-Junior, and C. S. F. Maia. “ Ganoderma Lucidum Ameliorates Neurobehavioral Changes and Oxidative Stress Induced by Ethanol Binge Drinking. ” Oxid Med Cell Longev 2020 (2020): 2497845. https://dx.doi.org/10.1155/2020/2497845
Oluba, O. M., O. B. Akpor, F. D. Adebiyi, S. J. Josiah, O. O. Alabi, A. O. Shoyombo, and A. O. Olusola. “ Effects of Co-Administration of Ganoderma Terpenoid Extract with Chloroquine on Inflammatory Markers and Antioxidant Status in Plasmodium Berghei-Infected Mice. ” J Integr Med (Aug 13 2020). https://dx.doi.org/10.1016/j.joim.2020.08.002
Rahman, M. A., S. Hossain, N. Abdullah, and N. Aminudin. “ Lingzhi or Reishi Medicinal Mushroom, Ganoderma Lucidum (Agaricomycetes) Ameliorates Spatial Learning and Memory Deficits in Rats with Hypercholesterolemia and Alzheimer’s Disease. ” Int J Med Mushrooms 22, no. 1 (2020): 93-103. https://dx.doi.org/10.1615/IntJMedMushrooms.2020033383
Lithothamnium-Alge
Haiyuan Wang et al., "A comparative study of calcium absorption following a single serving administration of calcium carbonate powder versus calcium citrate tablets in healthy premenopausal women", Food & Nutrition Research, 2014, (Eine Vergleichsstudie)
Ishitani K et al.,"Calcium absorption from the ingestion of coral-derived calcium by humans." J Nutr Sci Vitaminol (Tokyo). 1999 Oct;45(5):509-17. (Kalzium-Absorption von Korallen Kalzium während der Verdauung beim Menschen.)
Sakhaee et al., Meta-analysis of calcium bioavailability: a comparison of calcium citrate with calcium carbonate., American Journal of Therapeutics, November 1999, ("Meta-Analyse von Kalziumbioverfügbarkeit: ein Vergleich von Kalziumcitrat mit Kalziumcarbonat
Calcium Citrate Shown to Have Superior Bioavailability and Protects Against Bone Loss, Medscape Medical News, November 2000
Heller HJ et al, Pharmacokinetic and pharmacodynamic comparison of two calcium supplements in postmenopausal women., Journal of Clinical Pharmacology
Kimberly Johnson, The Many Forms of Calcium, Community Food Coop, Februar 2011, ("Die vielen Kalziumarten")
Calcium Absorption Test Results, CEVA, Februar 2007, (Kalziumresorption Testergebnisse)
Gaby Kressel, Bioavailability and Solubility of Different Calcium-Salts as a Basis for Kalzium Enrichment of Beverages, Scientific Research, Oktober 2010, ("Bioverfügbarkeit und Löslichkeit von verschiedenen Kalziumsalzen als Basis für kalziumangereichert
Robert Hanzlik et al., Relative Bioavailability of Calcium from Calcium Formate, Calcium Citrate, and Calcium Carbonate, The Journal of Pharmacology, Juni 2005, ("Relative Bioverfügbarkeit von Kalziumformat, Kalziumcitrat und Kalziumcarbonat")
Aloia JF et al., Vitamin D supplementation increases calcium absorption without a threshold effect, American Journal of Clinical Nutrition, Juli 2014, (Nahrungsergänzung mit Vitamin D erhöht Kalziumresorption ohne Grenzen)
Löwenzahn
Menghini L et al., Antiproliferative, protective and antioxidant effects of artichoke, dandelion, turmeric and rosemary extracts and their formulation, Int J Immunopathol Pharmacol. 2010 Apr-Jun;23(2):601-10
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Sigstedt SC et al., Evaluation of aqueous extracts of Taraxacum officinale on growth and invasion of breast and prostate cancer cells, Int J Oncol. 2008 May;32(5):1085-90
Jiang J et al., Suppression of growth and invasive behavior of human prostate cancer cells by ProstaCaid: mechanism of activity, Int J Oncol. 2011 Jun;38(6):1675-82
Ovadje P et al., Selective induction of apoptosis through activation of caspase-8 in human leukemia cells (Jurkat) by dandelion root extract, J Ethnopharmacol. 2011 Jan 7;133(1):86-91. Epub 2010 Sep 16
Chatterjee SJ et al., The efficacy of dandelion root extract in inducing apoptosis in drug-resistant human melanoma cells, Evid Based Complement Alternat Med. 2011;2011:129045. Epub 2010 Dec 30
Hata K, Ishikawa K, Hori K, Konishi T, Differentiation-inducing activity of lupeol, a lupane-type triterpene from Chinese dandelion root (Hokouei-kon), on a mouse melanoma cell line.Biol Pharm.Bull.2000
Ovadje P, Chochkeh M, Akbari-Asl P, et al, Selective induction of apoptosis and autophagy through treatment with dandelion root extract in human pancreatic cancer cells, Pancreas
Ovadje P, Ammar S, Guerrero JA, et al.Dandelion root extract affects colorectal cancer proliferation and survival through the activation of multiple death signalling pathways.Oncotarget., 2016, August
Ovadje P, Hamm C, Pandey S.Efficient induction of extrinsic cell death by dandelion root extract in human chronic myelomonocytic leukemia (CMML) cells, PLoS One, 2012
Barnes J, Anderson LA, Phillipson JD. Herbal Medicines. London: Pharmaceutical Press, 2002
Bensky D, Gamble A. Chinese Herbal Medicine, Materia Medica. Seattle: Eastland Press, Inc, 1993
Clare BA et al, The diuretic effect in human subjects of an extract of Taraxacum officinale folium over a single day., Journal of Alternative and Complementary Medicine, 2009 Aug;15(8):929-34
Cho AS et al, Chlorogenic acid exhibits anti-obesity property and improves lipid metabolism in high-fat diet-induced-obese mice., Food and Chemical Toxicology, 2010 Mar;48(3):937-43
Koh YJ et al, Anti-inflammatory effect of Taraxacum officinale leaves on lipopolysaccharide-induced inflammatory responses in RAW 264.7 cells., Journal of Medicinal Food, 2010 Aug;13(4):870-8
Park CM et al, TOP 1 and 2, polysaccharides from Taraxacum officinale, inhibit NF? B-mediated inflammation and accelerate Nrf2-induced antioxidative potential through the modulation of PI3K-Akt signaling pathway in RAW 264.7 cells., Food and Chemical Toxicology, 2014 Apr;66:56-64
Ma C et al, Anti-inflammatory effects of water extract of Taraxacum mongolicum hand.-Mazz on lipopolysaccharide-induced inflammation in acute lung injury by suppressing PI3K/Akt/mTOR signaling pathway., Journal of Ethnopharmacology, 2015 Jun 20;168:349-55
He W et al, Anti-influenza virus effect of aqueous extracts from dandelion, Virology Journal, 2010
Jin YR et al, The effect of Taraxacum officinale on gastric emptying and smooth muscle motility in Rodents., Neurogastroenterology and Motility, 2011 Aug;23(8):766-e333
Colle D et al, Antioxidant properties of Taraxacum officinale leaf extract are involved in the protective effect against hepatoxicity induced by acetaminophen in mice., Journal of Medicinal Food, 2012 Jun;15(6):549-56
Davaatseren M et al, Taraxacum official (dandelion) leaf extract alleviates high-fat diet-induced nonalcoholic fatty liver., Food and Chemical Toxicology, 2013 Aug;58:30-6.
Jia YY et al, Taraxacum mongolicum extract exhibits a protective effect on hepatocytes and an antiviral effect against hepatitis B virus in animal and human cells., Molecular Medicine Reports, 2014 Apr;9(4):1381-7
González-Castejón M et al, Diverse biological activities of dandelion., Nutrition Reviews, 2012 Sep;70(9):534-47
Ovadie P et al, Selective induction of apoptosis and autophagy through treatment with dandelion root extract in human pancreatic cancer cells., Pancreas, 2012 Oct;41(7):1039-47
Ovadie P et al, Dandelion root extract affects colorectal cancer proliferation and survival through the activation of multiple death signalling pathways., Oncotarget, 2016 Nov 8;7(45):73080-73100
Kenny O et al, Characterisation of antimicrobial extracts from dandelion root (Taraxacum officinale) using LC-SPE-NMR., Phytotherapy Research, 2015 Apr;29(4):526-32.
Diaz K et al, Isolation and Identification of Compounds from Bioactive Extracts of Taraxacum officinale Weber ex F. H. Wigg. (Dandelion) as a Potential Source of Antibacterial Agents., Evidence-Based Complementary and Alternative Medicine, 2018 Jan 1;2018:2706417.
Cho JW et al, Skin Hydration and Collagen Synthesis of AF-343 in HS68 Cell Line and NC/Nga Mice by Filaggrin Expression and Suppression of Matrix Metallopreteinase, Toxicology Research, 2011 Dec; 27(4): 225–229.
Warashina T et al, Constituents from the roots of Taraxacum platycarpum and their effect on proliferation of human skin fibroblasts., Chemical & Pharmaceutical Bulletin, 2012;60(2):205-12
Yang Y et al, Dandelion Extracts Protect Human Skin Fibroblasts from UVB Damage and Cellular Senescence., Oxidative Medicine and Cellular Longevity, 2015;2015:619560
Wirngo FE et al, The Physiological Effects of Dandelion (Taraxacum Officinale) in Type 2 Diabetes, Journal of the Society for Biomedical Diabetes Research, 2016; 13(2-3): 113–131
Jedrejek D et al, Evaluation of antioxidant activity of phenolic fractions from the leaves and petals of dandelion in human plasma treated with H2O2 and H2O2/Fe., Chemico-biological interactions, 2017 Jan 25;262:29-37
Lis B et al, Assessment of effects of phenolic fractions from leaves and petals of dandelion in selected components of hemostasis., Food Research International, 2018 May;107:605-612
Jedrejek D et al, Comparative phytochemical, cytotoxicity, antioxidant and haemostatic studies of Taraxacum officinale root preparations., Food and Chemical Toxicology, 2019 Apr;126:233-247
Liu Q et al, Effects of Dandelion Extract on the Proliferation of Rat Skeletal Muscle Cells and the Inhibition of a Lipopolysaccharide-Induced Inflammatory Reaction, Chinese Medical Journal, 2018 Jul 20; 131(14): 1724–1731
Lucuma
Guttierrez-Orozco, F.; Yahia, E.M.: "18 - Lucuma (Pouteria lucuma (Ruiz and Pav. Kuntze)", in: "Postharvest Biology and Technology of Tropical and Subtropical Fruits Cocona to Mango Woodhead Publishing Series in Food Science, Technology and Nutrition", 2011, sciencedirect.com
Wolfe, David: Superfoods - die Medizin der Zukunft: Wie wir die machtvollsten Heiler unter den Nahrungsmitteln optimal nutzen, Goldmann Verlag, 2015
Fuentealba, Claudia et al.: "Characterization of main primary and secondary metabolites and in vitro antioxidant and antihyperglycemic properties in the mesocarp of three biotypes of Pouteria lucuma", in: Food Chemistry, Volume 190, January 2016
Da Silva Pinto, Marcia et al.: "Evaluation of antihyperglycemia and antihypertension potential of native Peruvian fruits using in vitro models", in: Journal of Medicinal Food, Vol. 12 No. 2, 2009, liebertpub.com
Dini, Irene: "Flavonoid glycosides from Pouteria obovata (R. Br.) fruit flour", in: Food Chemistry, 124(3), February 2011, sciencedirect.com
Rojo, Leonel E. et al.: "Original Contribution: Wound-healing properties of nut oil from Pouteria lucuma", in: Journal of Cosmetic Dermatology, Volume 9, Issue 3, September 2010, Wiley Online Library
Pinto Mda S et al., Evaluation of antihyperglycemia and antihypertension potential of native Peruvian fruits using in vitro models, J Med Food, April 2009, (Die Bestätigung vom antihyperglykämischen und antihypertensischen Potenzial von peruanischen Früchten im Reagenzglas Modell)
Fuentealba C et al., Characterization of main primary and secondary metabolites and in vitro antioxidant and antihyperglycemic properties in the mesocarp of three biotypes of Pouteria lucuma, Food Chem, Januar 2016, (Charakterisierung von primren und sekundren Metaboliten sowie antioxidative und antihyperglykmische in vitro Eigenschaften aus dem Fruchtgehäuse von 3 Arten der peruanischen Lucuma Frucht)
Rojo LE et al., Wound-healing properties of nut oil from Pouterialucuma, J Cosmet Dermatol., September 2010, (Wundheilende Eigenschaften des Lucumakernls)
B. Ellen, 10 Great Reasons To Love Lucuma, (10
grossartige Gründe, Lucuma zu
lieben)
Mariendistel
Kalantari H. et al. (2011), Effects of silybum marianum on patients with chronic hepatitis C
Darvishi-Khezri H., et al. (2017), The impact of silymarin on antioxidant and oxidative status in patients with ß-thalassemia major: A crossover, randomized controlled trial
Hao-Jie Z., et al. (2013), An Assessment of Pharmacokinetics and Antioxidant Activity of Free Silymarin Flavonolignans in Healthy Volunteers: A Dose Escalation Study
Kawaguchi-Suzuki M., et al. (2014), The Effects of Milk Thistle (Silybum marianum on Human Cytochrome P450 Activity
Wilasrusmee C., et al. (2002), Immunostimulatory effect of Silybum Marianum (milk thistle) extract.
MCT
1. Deutsche Gesellschaft für Ernährung. (2011): Mittelkettige Triglyceride für die Adipositastherapie nicht empfehlenswert: 18-21.
2. Berning JR. (1996):The role of medium-chain triglycerides in exercise. Int J Sport Nutr. 6(2): 121-33.
3. Wang, Y., et al. (2018): Medium Chain Triglycerides enhances exercise endurance through the increased mitochondrial biogenesis and metabolism. PloS one.
4. Koji Nagao, Teruyoshi Yanagita. (2010): Medium-chain fatty acids: Functional lipids for the prevention and treatment of the metabolic syndrome. Pharmacological Research. Volume 61, Issue 3, Pages 208-212.
5. Papamandjaris, A.A., M.D. White, and P.J. Jones. (1999): Enhanced postprandial energy expenditure with medium-chain fatty acid feeding is attenuated after 14 d in premenopausal women. The American Journal of Clinical Nutrition. 69(5): p. 883-889.
6. Tosiaki Aoyama et al. (2007): Research on the nutritional characteristics of medium chain fatty acids. In: J. Med. Invest. 54(3-4). S. 385–388.
7. James E Galvin. (2012): Optimizing diagnosis and management in mild-to-moderate Alzheimer’s disease. NEURODEGENERATIVE DISEASE MANAGEMENT. VOL. 2, NO. 3.
8. A Herrmann. K W Jauch. B Günther. F W Schildberg. (1990): Elimination and Metabolism of MCT-containing Fat Emulsions in Postoperative Patients in the Framework of Total Parenteral Nutrition: 185-90; 193-6.
9. Y Kuge. K Yajima. H Kawashima. H Yamazaki. N Hashimoto. Y Miyake. (1995): Uptake and Metabolism of [1-11C]octanoate in Rats: Pharmacokinetic Basis for Its Application as a Radiopharmaceutical for Studying Brain Fatty Acid Metabolism. 137-42. doi: 10.1007/BF03165040.
10. Herbert Havera. (2020): MCT Öl – Wirkung, Inhaltsstoffe, Anwendung und Studien.
11. Laurene Boateng. Richard Ansong. William B Owusu . Matilda Steiner-Asiedu. (2016): Coconut Oil and Palm Oil's Role in Nutrition, Health and National Development: A Review. 189-196.
12. Taylor C Wallace. (2019): Health Effects of Coconut Oil-A Narrative Review of Current Evidence. 97-107. doi: 10.1080/07315724.2018.1497562.
Melatonin
1. Circadin® - eine Zusammenfassung der EMEA (PDF)
2. Leitlinie Clusterkopfschmerz der Deutschen Gesellschaft für Neurologie
3. British Medical Journal: Efficacy and safety of exogenous melatonin for secondary sleep disorders and sleep disorders accompanying sleep restriction: meta-analysis. BMJ 2006;332:385-393. PMID 16473858
Arendt J, Touitou Y: Melatonin and the Pineal Gland: From Basic Science to Clinical Application
Elsevier Science 1993, ISBN 0-4448-9583-3 (wissenschaftliches Standardwerk zu Melatonin)
Susan M. Webb, Manuel Puig-Domingo: Role of melatonin in health and disease. Clinical Endocrinology (1995) 42, 221-234.
Arnold Hilgers, Inge Hoffmann: Melatonin. Mosaik Verlag, München 1996, ISBN 3-5761-0622-7
Milchsäurebakterien
Johnston BC et al., Probiotics for the prevention of pediatric antibiotic-associated diarrhea, Cochrane Database Syst Rev, April 2007
Deepika Priyadarshani et al., Screening selected strains of probiotic lactic acid bacteria for their ability to produce biogenic amines (histamine and tyramine), 2011, International Journal of Food Science & Technology.
Vittorio Capozzi, Pasquale Russo et al, Biogenic Amines Degradation by Lactobacillus plantarum: Toward a Potential Application in Wine, Front Microbiol, 2012
Thomas CM et al, Histamine Derived from Probiotic Lactobacillus reuteri Suppresses TNF via Modulation of PKA and ERK Signaling. PLoS ONE, 2012
Dev S et al, Suppression of histamine signaling by probiotic Lac-B: a possible mechanism of its anti-allergic effect, Journal of pharmacological sciences, 2008
Nivetha A et al., Mini review on role of ?-galactosidase in lactose intolerance, IOP Science, 2017
Weitere Artikel
Milchsäurebakterien von Lebensmitteln und ihre aktuelle Taxonomie
Stiles ME, Holzapfel WH. Int J Food Microbiol. 29. April 1997;36(1):1-29. doi: 10.1016/s0168-1605(96)01233-0. PMID: 9168311 Rezension.
Monteagudo-Mera A, Caro I, Rodríguez-Aparicio LB, Rúa J, Ferrero MA, García-Armesto MR. J Lebens-mittelschutz. 2011 Aug; 74 (8): 1379 & ndash; 86. doi: 10.4315/0362-028X.JFP-10-392. PMID: 21819671
Auswahl von Milchsäurebakterien aus brasilianischen Kefirkörnern zur möglichen Verwendung als Starter- oder probiotische Kulturen
Zanirati DF, Abatemarco M Jr, Sandes SHC, Nicoli JR, Nunes ÁC, Neumann E. Anaerobe. 2015 Apr; 32: 70–76. doi: 10.1016/j.anaerobe.2014.12.007. Epub 2014 Dez. 24. PMID: 25542841
Verwendung von Milchsäurebakterien zur Bekämpfung pathogener Mikroorganismen in Lebensmitteln
Hernández PE, Rodríguez JM, Cintas LM, Moreira WL, Sobrino OJ, Fernández MF, Sanz B. Mikrobiologie. 1993 Feb. 9 Spez.-Nr.: 37-48. PMID: 8484916 Rezension. Spanisch.
Wechselwirkungen zwischen Milchsäurestarter und probiotischen Bakterien, die für fermentierte Milchprodukte verwendet werden
Vinderola CG, Mocchiutti P, Reinheimer JA. J Molkerei Sci. 2002 Apr;85(4):721-9. doi: 10.3168/jds.S0022-0302(02)74129-5. PMID: 12018416
Mineralstoffe
MSM
Barrager E et al, "A multicentered, open-label trial on the safety and efficacy of methylsulfonylmethane in the treatment of seasonal allergic rhinitis", J. Altern Complement Med, April 2002, (Eine offene, multizentrische Studie über die Sicherheit und Wirksamkeit von Methylsulfonylmethan in der Behandlung von saisonaler allergischer Rhinitis)
"Allergische Rhinitis plagt Betroffene oft das ganze Jahr", Ärzte Zeitung, Juni 2005
Patrick McGean, "The Live Blood and Cellular Matrix Study", (Die Lebendblut- und Zellmatrix-Studie)
Ethan A. Huff, "Organic sulfur crystals are a miracle food that provides amazing health benefits", Natural News, Juli 2010, (Organische Schwefelkristalle sind ein Wundermittel, das für erstaunliche gesundheitliche Vorteile sorgt)
Lim EJ et al, "Methylsulfonylmethane suppresses breast cancer growth by down-regulating STAT3 and STAT5b pathways", PLoS One, Juli 2012, (Methylsulfonylmethan unterdrückt das Wachstum von Brustkrebs durch herunterregulierte STAT3 und STAT5b Pfade)
Kim YH, "The anti-inflammatory effects of methylsulfonylmethane on lipopolysaccharide-induced in-flammatory responses in murine macrophages", Biol Pharm Bull, April 2009, (Die entzündungshem-mende Wirkung von Methylsulfonylmethan auf lipopolysaccharidinduzierte entzündliche Reaktionen bei mäusespezifischen Makrophagen)
Xie Q et al, "Effects of AR7 Joint Complex on arthralgia for patients with osteoarthritis: results of a three-month study in Shanghai, China", Nutr J, Oktober 2008, (Die Wirkungen von AR7 Joint Complex auf Arthralgie bei Patienten mit Osteoarthritis: Die Resultate einer dreimonatigen Studie in Shanghai, China)
Usha PR et al, "Randomised, Double-Blind, Parallel, Placebo-Controlled Study of Oral Glucosamine, Me-thylsulfonylmethane and their Combination in Osteoarthritis", Clin Drug Invest, Juni 2004, (Randomisier-te, plazebokontrollierte, Doppelblind-Parallel-Studie zu oral verabreichtem Glucosamin, Methylsul-fonylmethan und dessen Kombination bei Osteoarthritis)
Kim LS, "Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical tri-al", Osteoarthritis Cartilage, Mrz 2006, (Die Wirksamkeit von MSM bei osteoarthritischen Knieschmerzen: Eine klinische Pilotstudie)
Parcell S, "Sulfur in human nutrition and applications in medicine", Altern Med Rev, Februar 2002, (Schwefel in der menschlichen Ernährung und Anwendungen in der Medizin)
Joung, Youn Hee et al, "MSM Enhances GH Signaling via the Jak2/STAT5b Pathway in Osteoblast-like Cells and Osteoblast Differentiation through the Activation of STAT5b in MSCs", PLoS ONE, Oktober 2012, (MSM verbessert via dem Jak2/STAT5b-Stoffwechselweg das GH-Signaling in osteoblastenartigen Zellen und die Osteoblasten-Differenzierung durch die Aktivierung von STAT5b in MSCs)
Caron JM et al, "Methyl Sulfone Blocked Multiple Hypoxia- and Non-Hypoxia-Induced Metastatic Targets in Breast Cancer Cells and Melanoma Cells", PLoS One. November 2015, (Methylsulfon blockiert multiple durch Hypoxie und nicht durch Hypoxie verursachte metastatische Targets in Brustkrebszellen und Melanomzellen)
Barmaki S et al, "Effect of methylsulfonylmethane supplementation on exercise - Induced muscle dama-ge and total antioxidant capacity", J Sports Med Phys Fitness, April 2012, (Wirkung der Nahrungsergänzung mit Methylsulfonylmethan auf sportinduzierte Muskelschäden und die totale antioxidative Kapazi-tät)
Nakhostin-Roohi B et al, "Effect of chronic supplementation with methylsulfonylmethane on oxidative stress following acute exercise in untrained healthy men", J Pharm Pharmacol, Oktober 2011, (Auswirkung der chronischen Nahrungsergänzung mit MSM auf oxidativen Stress nach körperlicher Betätigung bei untrainierten, gesunden Männern)
Kalman DS, "Influence of methylsulfonylmethane on markers of exercise recovery and performance in healthy men: a pilot study", J Int Soc Sports Nutr, September 2012, (Der Einfluss von MSM auf Biomarker zur Regeneration sowie auf die Leistungsfähigkeit gesunder Männer: Eine Pilotstudie)
Fleck CA, "Managing ichthyosis: a case study", Ostomy Wound Manage, April 2006, (Ichthyose man-agen: eine Fallstudie)
Berardesca E et al, "Combined effects of silymarin and methylsulfonylmethane in the management of rosacea: clinical and instrumental evaluation", J Cosmet Dermatol, März 2008, (Kombinierte Wirkungen von Silymarin und Methylsulfonylmethan beim Management von Rosacea: Eine klinische und appa-rative Bewertung)
Medizin transparent: Hilft MSM bei Arthrose? Stand 15.12.2016. Zugriff 05.03.2020
National Center for Complementary and Integrative Health (NIH): Dimethyl Sulfoxide (DMSO) and Me-thylsulfonylmethane (MSM) for Osteoarthritis. Stand: 24.09.2017, Zugriff 05.03.2020 In: Gute Pillen schlechte Pillen, Heft 2/2013Zugriff 05.03.2020
EFSA (2010) Scientific Opinion on the substantiation of health claims related to Methylsulphonylme-thane (MSM) (...); EFSA Journal 2010;8(10):1746. Zugriff 05.03.2020
Arbeitskreis Lebensmittelchemischer Sachverständiger: Stellungnahme 2016/42: Gelenkpräparate als Nahrungsergänzungsmittel mit zugelassenen gesundheitsbezogenen Angaben in Bezug zu Bindegewebe, Knorpel oder Knochen.
Studien zu organischem Schwefel
MSM mit Glucosamin bei Arthrose: https://www.ncbi.nlm.nih.gov/pubmed/17516722
Antioxidative Kapazität von organischem Schwefel: https://www.ncbi.nlm.nih.gov/pubmed/22525653
Studie über den Einsatz bei Knieschmerzen: https://www.ncbi.nlm.nih.gov/pubmed/16309928
Einsatz bei Entzündungen: https://www.ncbi.nlm.nih.gov/pubmed/19336900
MSM in der Krebsforschung: https://www.ncbi.nlm.nih.gov/pubmed/22485142?dopt=Abstract
Myrrhe
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3. Blaschek W. et al. (Hrsg.): Hagers Handbuch der Drogen und Arzneistoffe, Springer-Verlag Heidelberg, 2004
4. Bubenzer, R.H. und Kaden, M.: Myrrhe : BGA Kommission-E-Monographien, Heftnummer: 193., ATC-Code: A01AF., Heilpflanzen Welt, multi MED vision GbR, Stand 15.10.1987
5. Dolara P. et al.: Local anaesthetic, antibacterial and antifungal properties of sesquiterpenes from myrrh. Planta Med. 2000 May;66(4):356-8.
6. Fathy FM.: Effect of mirazid (Commiphora molmol) on experimental giardiasis. J Egypt Soc Parasitol. 2011 Apr;41(1):155-77
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13. Rahman MM. et al.: Antibacterial terpenes from the oleo-resin of Commiphora molmol (Engl.). Phytother Res. 2008 Oct;22(10):1356-60
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16. Su S. et al.: Evaluation of the anti-inflammatory and analgesic properties of individual and combined extracts from Commiphora myrrha, and Boswellia carterii. J Ethnopharmacol. 2012 Jan 31;139(2):649-56
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20. World Health Organization, Geneva, 2007
21. Yousefi M. et al.: Clinical Evaluation of Commiphora Mukul, a Botanical resin, in the Management of Hemorrhoids: A randomized controlled trial. Pharmacogn Mag. 2013 Oct;9(36):350-6
Natriumbicarbonat
Sarah C. Ray, Paul M. OConnor, Oral NaHCO3 Activates a Splenic Anti-Inflammatory Pathway: Evidence That Cholinergic Signals Are Transmitted via Mesothelial Cells. The Journal of Immunology, 2018
Medical College of Georgia at Augusta University, Drinking baking soda could be an inexpensive, safe way to combat autoimmune disease: A daily dose of baking soda may help reduce the destructive inflammation of autoimmune diseases like rheumatoid arthritis<
Nattokinase
Nattokinase: A Promising Alternative in Prevention and Treatment of Cardiovascular Diseases
Nattokinase: An Oral Antithrombotic Agent for the Prevention of Cardiovascular Disease
Nattokinase Atherothrombotic Prevention Study (NAPS)
Effects of Nattokinase on Blood Pressure: A Randomized, Controlled Trial
Nattokinase – Hier wissenschaftlich fundiert: Fakten, Studien & Bewertung
[1] Kurosawa u.a. (2015)
Kurosawa Y, Nirengi S, Homma T, Esaki K, Ohta M, Clark JF, Hamaoka T. A single dose of oral nattokinase potenti-ates thrombolysis and anti-coagulation profiles. Sci Rep. 2015 Jun 25; 5:11601.
[2] Watanabe u.a. (2018)
Watanabe N, Takaoka S, Uehara S, Ohta M. Effect of nattokinase on the blood flow improvement in healthy sub-jects-a randomized, placebo-controlled, double-blind, cross-over study. Japanese pharmacology and therapeutics, 2018, 46(10), 1739‐1748
[3] Yoo u.a. (2019)
Yoo HJ, Kim M, Kim M, Lee A, Jin C, Lee SP, Kim TS, Lee SH, Lee JH. The effects of nattokinase supplementation on collagen-epinephrine closure time, prothrombin time and activated partial thromboplastin time in nondiabetic and hypercholesterolemic subjects. Food Funct. 2019 May 22;10(5):2888-2893.
[4] Arznei-Telegramm (2011)
Blutungsrisiko unter Nattokinase (DR. HITTICH NATTOPLASMIN) plus Phenprocoumon (MARCUMAR u.a.) Abgerufen am 11.7.2019
[5] Chang u.a. (2008)
Chang YY, Liu JS, Lai SL, Wu HS, Lan MY. Cerebellar hemorrhage provoked by combined use of nattokinase and aspirin in a patient with cerebral microbleeds. Intern Med. 2008;47(5):467-9.
[6] Chen u.a. (2018)
Chen H, McGowan EM, Ren N, Lal S, Nassif N, Shad-Kaneez F, Qu X, Lin Y. Nattokinase: A Promising Alternative in Prevention and Treatment of Cardiovascular Diseases. Biomark Insights. 2018 Jul 5;13:1177271918785130.
[7] Selvarajan & Bhatnagar (2017)
Selvarajan E, Bhatnagar N. Nattokinase: an updated critical review on challenges and perspectives. Cardiovasc Hematol Agents Med Chem. 2017 Dec
[8] Dabbagh u.a. (2014)
Dabbagh F, Negahdaripour M, Berenjian A, Behfar A, Mohammadi F, Zamani M, Irajie C, Ghasemi Y. Nattokinase: production and application. Appl Microbiol Biotechnol. 2014 Nov;98(22):9199-206.
[9] Weng u.a. (2017)
Weng Y, Yao J, Sparks S, Wang KY. Nattokinase: An Oral Antithrombotic Agent for the Prevention of Cardiovascu-lar Disease. Int J Mol Sci. 2017 Feb 28;18(3). pii: E523.
[10] Jensen u.a. (2016)
Jensen GS, Lenninger M, Ero MP, Benson KF. Consumption of nattokinase is associated with reduced blood pres-sure and von Willebrand factor, a cardiovascular risk marker: results from a randomized, double-blind, placebo-controlled, multicenter North American clinical trial. Integr Blood Press Control. 2016 Oct 13;9:95-104.
[11] Gesundheitsinformation.de (2017)
Was sind Blutverdünner (Gerinnungshemmer) und wie werden sie angewendet? Abgerufen am 11.7.2019
Okra
Yanti,Health Benefits of Okra Plant Best Healthy Foods 2012 (Gesundheitliche Vorteile durch Okra)
Oshims Herbal Online Pharmacy 2012 Okra
Fit Gesund Schön 2012 Okra - Schoten frisch gegart gesund und gehaltvoll
Ratschlag 24 2009 Mit Gemüse heilen: Okra
Wiedlack A., Okra exotisches Gemüse aus ÄthiopienEnjoy Living 2012
Universität Düsseldorf 2012 Okra als Heilpflanze
Milhahn K.,Ballaststoffe. Futter für den DarmStern 2012
Olivenblattextrakt
Über das Oleuropein in der Olive und seinen pharmakologischen Wirkungen
Autor: Syed Haris Omar. College of Pharmacy, Qassim University, P.O. Box-31922, Buraidah-51418, Saudi Arabia 2009. „Oleuropein in olive and its pharmacological effects.“, Sci Pharm. 2010;78(2):133-54.
Studie über den Mechanismus der antimikrobiellen Aktion des Oleuropeins
Autoren: B. Juven, Y. Heins, Jacoby. Abteilung für Lebensmitteltechnologie, Volcani-Institut für Agrarwissenschaften, Rehovot, Israel 1972.
Vergleichende Bewertung der antibakteriellen und antiparasitären Wirkungen einiger phenolischer Verbindungen in den Olivenbaumblättern
Autoren: NH. Aziz, S. Farad, L. Mousa, Abo Said. Nationales Zentrum für radioaktive Forschung und Technologie, Nasr City, Kairo 1998.
Antimikrobielle Aktivität des Oleuropeins und Hydroxytyrosols, in vitro gemessen
Autoren: G. Bisognano, A. Tomaino, R. Lo Cascio, G. Crisafi, N. Uccella, A. Kaija. Abteilung für Pharmazeutische Biologie der Universität von Messina, Italien 1999.
Antimykologische Aktivität des Oleuropeins, in vitro gemessen
Autoren: P. Furieri, A. Marino, A. Saija, N. Uccella, G. Bisognano. Wissenschaftliche Abteilung für Mikrobiologie und Gynäkologie, Universität von Catania, Catania, Italien 2002.
Antibakterielle Aktivität der Olivenbaumblätter, in vitro gemessen
Autoren: D. Markin, L. Duke, I. Berdicevsky. Abteilung für Mikrobiologie, Medizin-Fakultät Rapport, Technion, Technologie-Institut, Haifa, Israel 2003.
Regulierung einer Mikroorganismenflora mit Oliventresterextrakten
Über die Nutzung des Fungiziden und bakteriziden Potentials natürlicher Polyphenole zur Kontrolle von Pflanzenkrankheiten. Ein wissenschaftlicher Artikel des Institut für Lebensmitteltechnologie an der Universität Bonn. Veröffentlicht im Jahr 2003.
Aktivität gegen den HIV – Virus im Extrakt von Olivenbaumblättern
Autoren: J. Bao, DW. Zhang, JZ. Zhang, PL. Huang, S. Lee-Huang. Chemie – Fakultät, Universität New York, USA 2007.
Mechanismus der antiviralen Wirkung des Hydroxytyrosols auf die A-Grippeviren einschließlich H1N1, H3N2, H5N1, H9N2 und Subtypen
Autoren: K. Yamada, H. Ogawa, A. Hara, Y. Yoshida, Y. Yonezawa, K. Karibe, VB. Nghia, Y. Yoshimura Yamamoto, M. Yamata, K. Nakamura, K. Imai. Universität für Landwirtschaft und Medizin, Obihiro, Hokkaido, Japan 2009.
Oleuropein, in vitro und in vivo – Bewertung der antioxidativen Eigenschaften
Autoren: E. Speroni, MC. Guerra, A. Minghetti, N. Crespi-Perellino, P. Pasini, F. Piazza, A. Roda. Fakultät der Pharmazie der Universität von Bologna, Italien 1998.
Eigenschaft; die freien Radikalen durch die den Oliven-Polyphenolen eigenen Wirkungen, wegzukehren
Autoren: F. Visioli, G. Bellomo, C. Galli. Wissenschaftliche Fakultät für Biomedizin der Universität von Turin, Novara, Italien 1998.
Potenzielles Antioxidant/Antikrebsmittel der aus der Olive isolierten Phenolverbindungen
Autoren: RW. Owen, A. Giocosa, WE. Hull, R. Haubner, B. Spiegelhalder, H. Bartsch. Fachabteilung für Toxikologie, Krebsforschungszentrum Heidelberg, Deutschland 2000.
Antioxidative Wirkung der Polyphenole aus Olivenbaumblättern
Autoren: D. Markin, L. Duke, I. Berdicevsky. Abteilung für Mikrobiologie, Medizin-Fakultät Rapport, Technion, Technologie-Institut, Haifa, Israel 2000.
Quali/Quantitative Analyse über die antioxidativen Eigenschaften verschiedener aus den Olivenbaumblättern extrahierter Polyphenole*
Autoren: P. Pinelli, C. Galardi, N. Mulinacci, FF. Vincieri, M. Tattini, A. Romani. Abteilung für Pharmazeutische Wissenschaften der Universität von Florenz; Institut über die Vermehrung von Gehölzen CNR, Scandicci, Florenz, Italien 2000.
*Diese Forschung wurde vom MURST gesponsert (Ministerium für wissenschaftliche und technologische Forschung) und vom CNR (Nationaler Forschungsrat).
Olivenbaumblätter: Antioxidative Eigenschaften
Autoren: R. Briante, M. Patumi, S. Terenziani, E. Bismuto, F. Febbraio, R. Nucci. Enzymologie des CNR, Journal of Agricultural and Food Chemistry, Neapel, Italien 2002.
Vergleichende Untersuchung möglicher pro- oder antioxidativer Eigenschaften verschiedener Pflanzen-Phenole in vitro
Dissertation zur Erlangung des akademischen Grades, doctor medicinae (Dr. med.). Vorgelegt dem Rat der Medizinischen Fakultät der Friedrich-Schiller-Universität Jena von Dipl.-Med. Elisabeth Förstemann, Jena 2003.
Herz-Kreislauf-Aktivität der Extrakte junger Oliventriebe und Olivenbaumblätter
Autoren: C. Circosta, F. Occhiuto, A. Gregorio, S. Toigo, A. De Pasquale. Abteilung für Pharmazeutische Biologie der Universität von Messina, Italien 1990.
Die Gefäß erweiternden Wirkungen der Olivenbaumblätter
Autoren: Zarzuelo, J. Durante, J. Jimenez, M. Gonzalez, MP. Utrilla. Pharmakologie-Abteilung, Pharmazeutische Fakultät, Universität von Granada, Spanien 1991.
Arterielle Hypotonie, Hypoglykämie und Hypourizemie, festgestellt nach der wiederholten Verabreichung von wässrigen Olivenbaumblätter-Tees
Autoren: B. Fehri, JM. Aiache, A. Memmi, und andere. Département de Pharmacologie et de Toxicologie, Société des Industries Pharmacologique de Tunisie, Fondouk Choucha, Radès, Tunesien 1994.
Klinische Analyse über die Verwendung der wässrigen Olivenbaumblätter-Extrakte bei der Behandlung der arteriellen Hypertonie
Autoren: S. Cherif, N. Rahal, M. Haouala, B. Hizaoui, F. Dargouth, M. Guedicche, Z. Kallel, G. Balansard, K. Boukef. Abteilung für Kardiologie, Militärkrankenhaus von Tunis, Tunesien 1996.
Antioxidante Wirkung des LDL-Cholesterins bei der regelmäßigen Einnahme von phenolreichen Getränken
Autoren: M. Serafini, JA. Laranjinha, LM. Almeida, G. Maiani, Wissenschaftliches Labor über die Antioxidantien, Nationales Wissenschaftliches Institut für Lebensmittel- und Ernährungsforschung, Rom, Italien 2000.
Das Oleuropein beugt den durch Ischämie induzierten Verletzungen des Myokardiums vor
Autoren: C. Manna, V. Migliardi, P. Gollino, A. Scognamiglio, P. Galletti, M. Chiariello, V. Zoppia. Abteilung für Biochemie und Biophysik F. Cetrangolo, Medizin-Fakultät der zweiten Universität von Neapel, Italien 2004.
Weitere Literatur über den Olivenblattextrakt
Olivenbäume und die potenzielle Wirkung auf den menschlichen Organismus
Studie über Übergewicht
Studien aus Pakistan:
https://www.ncbi.nlm.nih.gov/pubmed/21501041
https://www.ncbi.nlm.nih.gov/pubmed/19135874
Bei Blutdruck
Omega 3
Burdge GC, Calder PC (2006) Di-etary alpha-linolenic acid and health-related outcomes: a metabolicperspective. Nutr Res Rev. 19: 26-522.
Stark AH, Crawford MA, Reifen R(2008) Update on alpha-linolenicacid. Nutr Rev. 66: 326–3323.
Hussein N, Ah-Sing E, Wilkinson P,Leach C, Griffin BA, Millward DJ(2005) Long-chain conversion of [C-13] linoleic acid and alpha-linolenicacid in response to marked changes intheir dietary intake in men. J LipidRes. 46: 269–2804.
Burdge GC, Wootton SA (2002) Conversion of alpha-linolenic acid to eicos-apentaenoic, docosapentaenoic and docosahexaenoic acids in young women. Br J Nutr. 88: 411–4205.
Burdge GC, Calder PC (2005) Conversion of alpha-linolenic acid to longer chain polyunsaturated fatty acids in human adults. Reprod Nutr. Dev. 45: 581–5976.
Pawlosky RJ, Hibbeln JR, Novotny JA,Salem N (2001) Physiological compartmental analysis of alpha-linolenicacid metabolism in adult humans. J Lipid Res. 42: 1257–12657.
Goyens PLL, Spilker ME, Zock PL,Katan MB, Mensink RP (2006) Con-version of alpha-linolenic acid in hu-mans is influenced by the absoluteamounts of alpha-linolenic acid and linoleic acid in the diet and not by their ratio. Am J Clin Nutr. 84: 44-538.
Burdge GC (2006) Metabolism ofalpha-linolenic acid in humans. Prostaglandins Leukot Essent FattyAcids. 75: 161–1689.
Gaßmann B (2006) Lipide. Ernährungs-Umschau. 53: 272–27810.
Bahri D, Gusko A, Hamm M, KasperH, Klor HU, Neuberger D, Singer P(2002) Significance and recommended dietary intake of long-chain omega-3 fatty acids – A consensusstatement of the omega-3 workinggroup. Ernährungsumschau. 49:94–9811.
Wolfram G. Ernährungssituation in Deutschland. Vortrag an der Nationalen Fachtagung der Schweizerischen Gesellschaft für Ernährung. Bern(2006)
Deutsche Gesellschaft für Ernährung, Österreichische Gesellschaft für Ernährung, Schweizerische Gesellschaft für Ernährungsforschung, Schweizerische Vereinigung für Ernährung. D.A.CH-Referenzwerte für die Nährstoffzufuhr. 1 Auflage, Umschau/Braus, Frankfurt (2000)
Institute of Medicine. Energy, carbohydrates, fiber, fat, fatty acids, cholesterol, protein, and amino acids. In: Dietary reference intakes. National Academies Press, Washington, DC (2002)14.
Barth CA, Erbersdobler HF (2006) Cardiovascular health and safety of rapeseed oil in human nutrition. Actual Ernährungsmed. 31: 211–21715.
Plourde M, Cunnane SC (2007) Extremely limited synthesis of long chain poly unsaturates in adults: implications for their dietary essentiality and use as supplements. Appl Physiol NutrMetab. 32: 619–63416.
Brouwer IA, Katan MB, Zock PL (2004) Dietary alpha-linolenic acid is associated with reduced risk of fatal coronary heart disease but increased prostate cancer risk: a metaanalysis. J Nutr. 134: 919–92217.
Egert S, Somoza V, Kannenberg F, Fobker M, Krome K, Erbersdobler HF,Wahrburg U (2007) Influence of three rapeseed oil-rich diets, fortified with alpha-linolenic acid, eicosapentaenoicacid or docosahexaenoic acid on the composition and oxidizability of low-density lipoproteins: results of a con-trolled study in healthy volunteers. Eur J Clin Nutr. 61: 314–32518.
Zhao GX, Etherton TD, Martin KR, West SG, Gillies PJ, Kris-Etherton PM (2004) Dietary alpha-linolenic acid reduces inflammatory and lipid cardiovascular risk factors in hypercho-lesterolemic men and women. J Nutr.134: 2991–299719.
Gurr MI. Role of fats in food and nu-trition. 2 Auflage, Elsevier Applied Science, London and New York (1999)20.
Connor WE (2000) Importance of n-3 fatty acids in health and disease. Am J Clin Nutr. 71: 171S–175S21.
Wang C, Harris WS, Chung M, Lichtenstein AH, Balk EM, Kupel-nick B, Jordan HS, Lau J (2006) n-3
OPC
https://www.ncbi.nlm.nih.gov/pubmed/19608210 Hier wurde den Patienten 150 mg – 300 mg OPC verabreicht. Tatsächlich konnte beobachtet werden, dass es durchaus zu einer Senkung des Blutdrucks kommen konnte.
Studie zur Prävention von Arteriosklerose: https://www.ncbi.nlm.nih.gov/pubmed/23176379
Studie zur antioxidativen Wirkung: https://www.ncbi.nlm.nih.gov/pubmed/9875688
Hier noch eine Studie die bei Patienten mit Diabetes Typ 2 durchgeführt wurde. Ebenfalls ein Humanversuch:https://www.ncbi.nlm.nih.gov/pubmed/19646193 Sehr interessant dabei ist, dass hier festgestellt wurde, dass OPC durchaus entzündungshemmend wirken könnte. Zudem beeinflusst es die glykämischen Parameter.
Studie zur Steigerung der Fließfähigkeit des Blutes Studie: https://www.ncbi.nlm.nih.gov/pubmed/16670692
Zudem hat OPC auch den Ruf eines Antioxidans . Auch hierzu gibt es natürlich auch eine Studie: https://www.ncbi.nlm.nih.gov/pubmed/16670692
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Papaya
Infos zu einer Studie bezüglich der natürlichen Wirkkraft: http://therapy.epnet.com/nat/GetContent.asp?siteid=EBSCO&chunkiid=21722
Studie über Wundheilung: https://www.ncbi.nlm.nih.gov/pubmed/23405827
Studie über Antioxidantien: http://www.sciencedirect.com/science/article/pii/S0308814606003426
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[2] Studien zeigen, dass Quinoa-Saponine ein entzündungshemmendes Potenzial haben, da sie die Freiset-zung von entzündlichen Zytokinen unterdrücken. Yao Y, Yang X, Shi Z, Ren G.: Anti-inflammatory activity of saponins from quinoa (Chenopodium quinoa Willd.) seeds in lipopolysaccharide-stimulated RAW 264.7 mac-rophages cells.; J Food Sci. 2014 May;79(5):H1018-23. doi: 10.1111/1750-3841.12425. Epub 2014 Apr 8.
[3] Tang Y, Li X, Zhang B, Chen PX, Liu R, Tsao R: Characterisation of phenolics, betanins and antioxidant activi-ties in seeds of three Chenopodium quinoa Willd. genotypes.; Food Chem. 2015 Jan 1;166:380-8. doi: 10.1016/j.foodchem.2014.06.018. Epub 2014 Jun 14.
[4] Vinarova L, Vinarov Z, Damyanova B, Tcholakova S, Denkov N, Stoyanov S.: Mechanisms of cholesterol and saturated fatty acid lowering by Quillaja saponaria extract, studied by in vitro digestion model.; Food Funct. 2015 Apr;6(4):1319-30. doi: 10.1039/c4fo01059k.
[5] AF Fidan et al.: The Effects of Yucca Schidigera and Quillaja Saponaria on DNA Damage, Protein Oxidation, Lipid Peroxidation, and Some Biochemical Parameters in Streptozotocin-Induced Diabetic Rats.; J Diabetes Complications 22 (5), 348-356. 2008 Apr 16. More.
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Seagreens® Ascophyllum nodosum
Studies in the Autecology of Ascophyllum Nodosum
Ecological studies of the salt marsh ecad scorpioides
Improved methods of analysis for betaines in Ascophyllum nodosum and its commercial seaweed extracts
Toward the molecular understanding of the action mechanism of Ascophyllum nodosum extracts on plants
DARK CARBON FIXATION STUDIES ON THE INTERTIDAL MACROALGA ASCOPHYLLUM NODOSUM (PHAEOPHYTA)
A MODEL FOR GAMETE RELEASE IN ASCOPHYLLUM NODOSUM (PHAEOPHYTA)
Sulfoxidation mechanism of vanadium bromoperoxidase from Ascophyllum nodosum
Bromine K-edge EXAFS studies of bromide binding to bromoperoxidase from Ascophyllum nodosum
PHYSIOLOGICAL STUDIES ON THE RELATIONSHIP BETWEEN ASCOPHYLLUM NODOSUM AND POLYSIPHONIA LANOSA
Optimization of Cu(II) biosorption onto Ascophyllum nodosum by factorial design methodology
Caenorhabditis elegans against oxidative and thermal stress
Some structural aspects of vanadium bromoperoxidase from Ascophyllum nodosum
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18. Ruitang Deng, Te-Jin Chow. Hypolipidemic, Antioxidant and Antiinflammatory Activities of Microalgae Spirulina.Cardiovasc Ther. Author manuscript; available in PMC 2011 Aug 1.
19. Mark F. McCarty. Clinical Potential of Spirulina as a Source of Phycocyanobilin. NutriGuard Research, Encinitas, California.
20. G. Puyfoulhoux, J.M. Rouanet, P. Besancon, B. Baroux, J.C. Baccou, and B. Caporiccio. Iron availability from iron-forti ed spirulina by an in vitro digestion/Caco-2 cell culture model.J. Agric. Food Chem., 2001, 49 (3), pp 1625–1629.
21. M. De, A. Halder, T. Chakraborty, U. Das, S. Paul, A. De, J. Banerjee, T. Chatterjee, and S. De. Incidence of anemia and effect of nutritional supplementation on women in rural and tribal populations of eastern and northeastern India. Hematology, Vol. 16, No. 3, pp. 190-192.
22. R. Kapoor and U. Mehta. Supplementary effect of spirulina on hematological status of rats during pregnancy and lactation.
23. Y. Wang, C.F. Chang, J. Chou, H.L. Chen, X. Deng, B.K. Harvey, J.L. Cadet, and P.C. Bickford. Dietary supplementation with blueberries, spinach, or spirulina reduces ischemic brain damage.Experimental Neurology, Vol. 193, No. 1, pp. 75-84.
24. A.D. Bachstetter, J. Jernberg, A. Schlunk, J.L. Vila, C. Hudson, M.J. Cole, R.D. Shytle, J. Tan, P.R. Sanberg, C.D. Sanberg, C. Borlongan, Y. Kaneko, N. Tajiri, C. Gemma, and P.C. Bickford. Spirulina promotes stem cell genesis and protects against LPS induced declines in neural stemcell proliferation. PLOS ONE, Vol. 5, No. 5.
25. M. Gargouri, F. Chorbel-Koubaa, M. Bonenfant-Magne, C. Magne, X. Dauvergne, R. Ksouri, Y. Krichen, C. Abdelly, and A. El Feki. Spirulina or dandelion-enriched diets of mothers alleviates lead-induced damages in brain and cerebellum of newborn rats.Food and Chemical Toxicology, Vol. 50, No. 7, pp. 2303-10.
26. N. Patro, A. Sharmam, K. Kariaya, and I. Patro. Spirulina platensis protects neurons via suppression of glial activation and peripheral sensitization leading to restoration of motor function in collagen-induced arthritic rats.Indian J Exp Biol. 2011 Oct;49(10):739-48.
27. J.H. Hwang, I.T. Lee, K.C. Jeng, M.F. Wang, R.C. Hou, S.M. Wu, and Y.C. Chang. Spirulina prevents memory dysfunction, reduces oxidative stress damage and augments antioxidant activity in senescence-accelerated mice.J Nutr Sci Vitaminol (Tokyo). 2011;57(2):186-91.
28. S. Thaakur and R. Sravanthi. Neuroprotective effect of spirulina in cerebral ischemia-reperfusion injury in rats. Journal of Neural Transmission, Vol. 117, No. 9, pp. 1083-91.
29. G. Chamorro, M. Perez-Albiter, N. Serrano-Garcia, J.J. Mares-Samano, and P. Rojas, P. Spirulina maxima pretreatment partially protects against 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine neurotoxicity. Nutritional Neuroscience, Vol. 9, No. 5-6, pp. 207-212.
30. M.F. McCarty, J. Barroso-Aranda, and F. Contreras. Oral phcocyanobilin may diminish the pathogenicity of activated brain microglia in neurodegenerative disorders.Medical Hypotheses, Vol. 74, No. 3, pp. 601-605.
31. S.H. Kim, C. Shin, S.K. Min, S.M. Jung, and H.S. Shin. In vitro evaluation of the effects of electrospun PCL nano ber mats containing the microalgae spirulina (Arthrospira) extract on primary astrocytes.
32. Mayada Ragab Farag, Mahmoud Alagawany, Mohamed Ezzat Abd El-Hack and Kuldeep Dhama. Nutritional and Healthical Aspects of Spirulina (Arthrospira) for Poultry,Animals and Human. Science Alert, 10.3923/ijp.2016.36.51.
33. E.P. Sabina, J. Samual, S. RajappaRamya, S. Patel, N. Mandal, P. Pranatharthiiharan, P.P. Mishra, and M.K. Rasool. Hepatoprotective and antioxidant potential of spirulina fusiformis on acetaminophen-induced hepatotoxicity in mice. Research Gate
34. P.V. Torres-Durán, R. Miranda-Zamora, M.C. Paredes-Carbajal, D. Mascher, J. Blé-Castillo, J.C. Díaz-Zagoya, M.A. Juárez-Oropeza. Studies on the preventive effect of spirulina maxima on fatty liver development induced by carbon tetrachloride, in the rat. J Ethnopharmacol. 1999 Feb;64(2):141-7.
35. O. Sinanoglu, A.N. Yener, S. Ekici, A. Midi, and F.B. Aksungar. The protective effects of spirulina in cyclophosphamide induced nephrotoxicity and urotoxicity in rats.Urology. 2012 Dec;80(6):1392.e1-6. doi: 10.1016.
36. Ferreira-Hermosillo A, Torres-Duran PV, Juarez-Oropeza MA. Hepatoprotective effects of Spirulina maxima in patients with non-alcoholic fatty liver disease: a case series.J Med Case Rep. 2010 Apr 7;4:103. doi: 10.1186/1752-1947-4-103.
37. P.V. Torres-Duran, A. Ferreira-Hermosillo, and M.A. Juarez-Oropeza. Antihyperlipidemic and antihypertensive effects of Spirulina maxima in an open sample of Mexican population: A preliminary report.Lipids in Health and Disease, Vol. 6, No. 33.
38. H.J. Park, Y.J. Lee, H.K. Ryu, M.H. Kim, H.W. Chung, and W.Y. Kim. A randomized double-blind, placebo-controlled study to establish the e ects of spirulina in elderly Koreans.Annals of Nutrition and Metabolism, Vol. 54, No. 4, pp. 322-328.
39. A. MICZKE, M. SZULINSKA, R. HANSDORFER-KORZON, M. KREGIELSKA-NAROZN, J. SULIBURSKA, J. WALKOWIAK,P. BOGDANSKI. Effects of spirulina consumption on body weight, blood pressure, and endothelial function in overweight hypertensive Caucasians: a double- blind, placebo-controlled, randomized trial.European Review for Medical and Pharmacological Sciences 2016; 20: 150-156.
40. Khan M, Varadharaj S, Shobha JC, Naidu MU, Parinandi NL, Kutala VK, Kuppusamy P. C-phycocyanin ameliorates doxorubicin-induced oxidative stress and apoptosis in adult rat cardiomyocytes.J Cardiovasc Pharmacol. 2006 Jan;47(1):9-20.
41. J. C. O. Sardi, L. Scorzoni, T. Bernardi, A. M. Fusco-Almeida and M. J. S. Mendes Giannini. Candida species: current epidemiology, pathogenicity, biofilm formation, natural antifungal products and new therapeutic options.Journal of Medical Microbiology (2013), 62, 10–24.
42. M.A. Pfaller and D. J. Diekema. Epidemiology of Invasive Candidiasis: a Persistent Public Health Problem. Clin Microbiol Rev. 2007 Jan; 20(1): 133–163.
43. Soltani M, Khosravi AR, Asadi F, Shokri H. Evaluation of protective efficacy of Spirulina platensis in Balb/C mice with candidiasis. J Mycol Med. 2012 Dec;22(4):329-34. doi: 10.1016.
44. El-Sheekh MM, Mahmoud YA, Abo-Shady AM, Hamza W. Efficacy of Rhodotorula glutinis and Spirulina platensis carotenoids in immunopotentiation of mice infected with Candida albicans SC5314 and Pseudomonas aeruginosa 35. Folia Microbiol (Praha). 2010 Jan;55(1):61-7. doi: 10.1007.
45. Ozdemir G, Karabay NU, Dalay MC, Pazarbasi B. Antibacterial activity of volatile component and various extracts of Spirulina platensis. Phytother Res. 2004 Sep;18(9):754-7.
46. Spirulina In The Candida Diet. Candida Diet Foods, May, 1 2010.
47. Teas J, Irhimeh MR. Dietary algae and HIV/AIDS: proof of concept clinical data. J Appl Phycol. 2012 Jun;24(3):575-582. Epub 2011 Dec 29.
48. Nicht mehr verfügbar
49. Fachartikel zur Bewertung von Spirulinas Wirksamkeit beim Einsatz gegen Krebszellen
50. Konícková R et al. Anti-cancer effects of blue-green alga Spirulina platensis, a natural source of bilirubin-like tetrapyrrolic compounds.Ann Hepatol. 2014 Mar-Apr;13(2):273-83.
51. Ichimura M, Kato S, Tsuneyama K, Matsutake S, Kamogawa M, Hirao E, Miyata A, Mori S, Yamaguchi N, Suruga K, Omagari K. Phycocyanin prevents hypertension and low serum adiponectin level in a rat model of metabolic syndrome. Nutr Res. 2013 May;33(5):397-405. doi: 10.1016/
52. Cheong SH, Kim MY, Sok DE, Hwang SY, Kim JH, Kim HR, Lee JH, Kim YB, Kim MR. Spirulina prevents atherosclerosis by reducing hypercholesterolemia in rabbits fed a high-cholesterol diet.J Nutr Sci Vitaminol (Tokyo). 2010;56(1):34-40.
53. Amy Norton. High-protein meals may help overweight burn fat.HEALTH NEWS NOVEMBER 24, 2008
54. Parikh P, Mani U, Iyer U. Role of Spirulina in the Control of Glycemia and Lipidemia in Type 2 Diabetes Mellitus. J Med Food. 2001 Winter;4(4):193-199.
55. Irene M Stratton, et al. Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study.BMJ 2000; 321, Published 12 August 2000.
56. Ou Y, Lin L, Pan Q, Yang X, Cheng X. Preventive effect of phycocyanin from Spirulina platensis on alloxan-injured mice.Environ Toxicol Pharmacol. 2012 Nov;34(3):721-6. doi: 10.1016/j.etap.2012.09.016. Epub 2012 Oct 8.
57. Jarouliya U, Zacharia JA, Kumar P, Bisen PS, Prasad GB. Alleviation of metabolic abnormalities induced by excessive fructose administration in Wistar rats by Spirulina maxima. Indian J Med Res. 2012 Mar;135:422-8.
58. How Many Fruits and Vegetables Do You Need? Centers for Disease Control and Prevention website. As of April 3, 2015.
59. Ronald H. Henson Spirulina Algae Improves Japanese Fish Feeds. Aquaculture Magazine, pp. 38-43.
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Triphala
http://wiki.yoga-vidya.de/Wissenschaftliche_Studien_Ayurveda
Studie über den möglichen Einsatz bei Krebs:
https://www.ncbi.nlm.nih.gov/pubmed/21138390?dopt=Abstract
Studie über Triphala und dermale Fibroblasten:
http://www.ncbi.nlm.nih.gov/pubmed/26731545
Studie bezüglich Lebererkrankungen:
http://www.ncbi.nlm.nih.gov/pubmed/26730147
Untersuchungen bezüglich des antioxidativen Potentials:
http://www.ncbi.nlm.nih.gov/pubmed/26731545
Weitere Literatur
Baliga, Manjeshwar Shrinath: "Triphala, Ayurvedic Formulation for Treating and Preventing Cancer: A Review", in: The Journal of Alternative and Complementary Medicine, Vol. 16 No. 12, 2010, liebertpub.com
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Khalsa, Karta Purkh Singh; Tierra, Michael: The Way of Ayurvedic Herbs: The Most Complete Guide to Natural Healing and Health with Traditional Ayurvedic Herbalism, Lotus Press, 2008
Rosenberg, Kerstin: Ayurveda kompakt: Heilkunst und Rezepte für Körper und Seele, Südwest Verlag, 2014
Varma, Sandeep R. et al.: "Protective Effects of Triphala on Dermal Fibroblasts and Human Keratinocytes", in: PLOS One, January 2006, PLOS One
Kumar, Muthusamy Senthil et al.: "Triphala promotes healing of infected full-thickness dermal wound", in: Journal of Surgical Research, Volume 144 Issue 1, January 2008, sciencedirect.com
Natsume, Yohko: "Tri-phala (Three Myrobalans) as Described in the Second Part of the Bower Manuscript, the Navanitaka", in: Yakushigaku zasshi. The Journal of Japanese history of pharmacy, 50(1), 2015, NCBI
Belapurkar, Pranoti et al.: "Immunomodulatory effects of triphala and its individual constituents: a review", in: Indian Journal of Pharmaceutical Science, 76(6), Nov-Dec 2014, NCBI
Vitamin B1 (Thiamin)
Depeint F., et al.(2006), Mitochondrialfunction and toxicity: role of the B vitamin family on mitochondrial energy metabolism
Song Q. et al. (2002), Mitochondria from cultured cells derived from normal and thiamine-responsive megaloblastic anemia individuals efficiently import thiamine diphosphate
Singleton C.K., et al. (2001), Molecular mechanisms of thiamine utilization
Vitamin B2 (Riboflavin)
Lodovica V., et. al. (1999), Riboflavin therapy: Biochemical heterogeneity in two adult lipid storage myopathies
David O. Kennedy (2016), B Vitamins and the Brain: Mechanisms, Dose and Efficacy—A Review
Sreenivas A. (2014), Treatment of Mitochondrial Disorders
Vitamin B3 (Niacin)
Real A. M. (2013), Nicotinamide N-Oxidation by CYP2E1 in Human Liver Microsomes
Osar Z., et al. (2004), Nicotinamide Effects Oxidative Burst Activity of Neutrophils in Patients with Poorly Controlled Type 2 Diabetes Mellitus
Li F., et al. (2006) Cell Life Versus Cell Longevity: The Mysteries Surrounding the NAD+ Precursor Nicotinamide
Hollis F., et al. (2015), Mitochondrial function in the brain links anxiety with social subordination
David O. Kennedy (2016), B Vitamins and the Brain: Mechanisms, Dose and Efficacy—A Review
J S Ungerstedt J.S., (2003), Nicotinamide is a potent inhibitor of proinflammatory cytokines
Real A. M. (2013), Nicotinamide N-Oxidation by CYP2E1 in Human Liver Microsomes
Osar Z. (2004), Nicotinamide Effects Oxidative Burst Activity of Neutrophils in Patients with Poorly Controlled Type 2 Diabetes Mellitus
Vitamin B6 (Pyridoxin)
Hodges R.H., et al. (2015), Modulation of Metabolic Detoxification Pathways Using Foods and Food-Derived Components: A Scientific Review with Clinical Application
Merrill AH Jr., et al. (1990), Vitamin B6 metabolism by human liver
Vitamin B9 (Methylfolin)
David O. Kennedy(2016), B Vitamins and the Brain: Mechanisms, Dose and Efficacy—A Review
Vitamin B12 (Methylcobalamin)
Al-Daghri N.M., et al. (2016), Association of Vitamin B12 with Pro-Inflammatory Cytokines and Biochemical Markers Related to Cardiometabolic Risk in Saudi Subjects
Fiona O’Leary, et al. (2010), Vitamin B12 in Health and Disease
Arzneimittel-Fachinformation (CH, D)
Goldsmith G.A. Vitamin B complex. Thiamine, riboflavin, niacin, folic acid (fola-cin), vitamin B12, biotin. Prog Food Nutr Sci, 1975, 1(9), 559-609
Lehrbücher der Pharmakotherapie
Semba R.D. The discovery of the vitamins. Int J Vitam Nutr Res, 2012, 82(5), 310-5
Sinclair H.M. The Vitamin B Complex. Postgrad Med J, 1941, 17(183), 3-12
Sneader W. Drug discovery: a history. Chichester: Wiley, 2005
Deutsche Gesellschaft für Ernährung: "Ausgewählte Fragen und Antworten zu Vi-tamin B12", unter: www.dge.de (Abruf: 07.10.2019)
Deutsche Gesellschaft für Ernährung: Referenzwerte - Vitamin B12, unter: www.dge.de (Abruf: 07.10.2019)
Elmfada, I. et al.: Die große GU Nährwert Kalorien Tabelle, Gräfe und Unzer Ver-lag, 2. Auflage, 2015
Klein, T.: Volkskrankheit Vitamin-B12-Mangel, Hygeia-Verlag, 9. Auflage, 2017
Pietrzik, K. et al.: Handbuch Vitamine, Urban & Fischer Verlag, 2008
Pschyrembel Online, Klinisches Wörterbuch: www.pschyrembel.de (Abruf: 07.10.2019)
Souci, S. W. et al.: Die Zusammensetzung der Lebensmittel, Nährwert-Tabellen, 8. Auflage, medpharm Scientific Publisher, 2016
Weihrauch
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3. Bertsche, T., Effekte polycyclischer Triterpene aus Boswellia spec. auf Mitogen-aktivierte Kinasen in neutrophilen Granulocyten und Glioblastoma-T98G-Zellen. Diss. Universität Tübingen 2001.
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5. Hoernlein, R. F., et al., Acetyl-11-keto-beta-boswellic acid induces apoptosis in HL-60 and CCRF-CEM cells and inhibits topoisomerase I. J. Pharmacol. Exp. Ther. 288 (1999) 613 - 619.
6. Safayhi, H., et al., Inhibition by boswellic acids of human leukocyte elastase. J. Pharmacol. Exp. Ther. 281 (1997) 460 - 463.
7. Wagner, H., et al., Pflanzeninhaltsstoffe mit Wirkung auf das Komplementsystem. Z. Phytother. 8 (1987) 148 - 149.
8. Boden, S. E., et al., Stimulation of leukotriene synthesis in intact polymorphonuclear cells by the 5-lipoxygenase inhibitor 3-oxo-tirucallic acid. Molecul. Pharmacol. 60 (2001) 267 - 273.
9. Etzel, R., Special extract of Boswellia serrata (H15) in the treatment of rheumatoid arthritis. Phytomed. 3 (1996) 91 - 94.
10. Sander, O., et al., Is H15 (resin extract of Boswellia serrata incense) a useful supplement to established drug therapy of chronic polyarthritis? Results of a double-blind pilot study. Z. Rheumatol. 57 (1998) 11 - 16.
11. Gupta, I., et al., Effects of Boswellia serrata gum resin in patients with ulcerative colitis. Eur. J. Med. Res. 2 (1997) 3743.
12. Gupta, I., et al., Effects of Boswellia serrata gum resin in patients with chronic colitis. Planta Med. 67 (2001) 391 - 395.
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14. Gupta, I., et al., Effects of Boswellia serrata gum resin in patients with bronchial asthma: results of a double-blind, placebo-controlled, 6-week clinical study. Eur. J. Med. Res. 3 (1998) 511 - 514.
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16. Weller, M., et al., Chemotherapie maligner Gliome. Nervenheilkunde 19 (2000) 116 - 120.
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Weitere Studien
Prabhavathi K. et al. (2014), A randomized, double blind, placebo controlled, cross over study to evaluate the analgesic activity of Boswellia serrata in healthy volunteers using mechanical pain model
Haroyan A., et al. (2018), Efficacy and safety of curcumin and its combination with boswellic acid in osteoarthritis: a comparative, randomized, double-blind, placebo-controlled study.
Geghelli et al. (2017), Antioxidant and Ex Vivo mmune System Regulatory Properties of Boswellia serrata Extracts
Gupta P. K. et al. (2011), Clinical evaluation of Boswellia serrata (Shallaki) resin in the management of Sandhivata(osteoarthritis)
Takada Y, et al. (2006), Acetyl-11-keto-beta-boswellic acid potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis by suppressing NF-kappa B and NF-kappa B-regulated gene expression
Weizengras
Chinesische Studie zur Auswirkung auf die Arterienverkalkung: http://www.ncbi.nlm.nih.gov/pubmed/21872250.
Israel Studie zu Brustkrebs: http://www.ncbi.nlm.nih.gov/pubmed/17571966.
Studie bei Darmerkrankungen: http://www.ncbi.nlm.nih.gov/pubmed/11989836
Wild Yam
1. DHU, Homöopathisches Repetitorium, Ausgabe 2001
2. C. M. Boger: Synoptic Key, Similimum-Verlag
3. A. Seideneder: Mitteldetails der homöopathischen Einzelmittel, Band 2, Similimum-Verlag
4. William Boericke: Handbuch der homöopathischen Materia medica, Haug-Verlag
5. http://de.wikipedia.org/wiki/Dioscorea_villosa
Yakón
Genta S1, Cabrera W, Habib N, Pons J, Carillo IM, Grau A, Sánchez S. Yacon syrup: beneficial effects on obesity and insulin resistance in humans. Clin Nutr. 2009 Apr; 28(2):182-7. https://www.ncbi.nlm.nih.gov/pubmed/19254816
de Moura NA, Caetano BF, Sivieri K, Urbano LH, Cabello C, Rodrigues MA, Barbisan LF. Protective effects of yacon (Smallanthus sonchifolius) intake on experimental colon carcinogenesis. Food Chem Toxicol. 2012 Aug; 50(8):2902-10. https://www.ncbi.nlm.nih.gov/pubmed/22595329
Caetano BF, de Moura NA, Almeida AP, Dias MC, Sivieri K, Barbisan LF., Yacon (Smallanthus sonchifolius) as a Food Supplement: Health-Promoting Benefits of Fructooligosaccharides. Nutrients. 2016 Jul 21;8(7).https://www.ncbi.nlm.nih.gov/pubmed/?term=Caetano+BF+et+al.%2C+Yacon+(Smallanthus+sonchifolius)+as+a+Food+Supplement%3A+Health-Promoting+Benefits+of+Fructooligosaccharides
de Souza Lima Sant’Anna M, Rodrigues VC, Araújo TF, de Oliveira TT, do Carmo Gouveia Peluzio M, de Luces Fortes Ferreira CLYacon-Based Product in the Modulation of Intestinal Constipation. J Med Food. 2015 Sep;18(9):980-6. https://www.ncbi.nlm.nih.gov/pubmed/25692980
Genta S, Cabrera W, Habib N, Pons J, Carillo IM, Grau A, Sánchez S. Yacon syrup: beneficial effects on obesity and insulin resistance in humans. Clin Nutr. 2009 Apr;28(2):182-7. https://www.ncbi.nlm.nih.gov/pubmed/19254816
Sugahara S, Ueda Y, Fukuhara K, Kamamuta Y, Matsuda Y, Murata T, Kuroda Y, Kabata K, Ono M, Igoshi K, Yasuda S., Antioxidant Effects of Herbal Tea Leaves from Yacon (Smallanthus sonchifolius) on Multiple Free Radical and Reducing Power Assays, Especially on Different Superoxide Anion Radical Generation Systems, J Food Sci. 2015 Nov;80(11):C2420-9. https://www.ncbi.nlm.nih.gov/pubmed/26457985
Zeolith
Associated Press, Levels of Radioactive Materials Rise Near Japanese Plant, The New York Times, 16. April 2011, (Radioaktive Werte nahe des japanischen Atomkraftwerks steigen)
Emmanouil Karampahtsis, Zeolite: Investigation of the Effectiveness and Safety as an Oral Chelating Agent for Heavy Metals. A comparison between different commercially available preparations, Dezember 2012, (Zeolith: Untersuchung der Wirksamkeit und Sicherheit als ein orales Chelatierungsagens für Schwermetalle. Ein Vergleich zwischen verschiedenen kommerziell erhältlichen Präperationen)
Flowers JL, et al, Clinical evidence supporting the use of an activated clinoptilolite suspension as an agent to increase urinary excretion of toxic heavy metals, Nutrition and Dietary Supplements, 4 November 2009, (Klinischer Beweis unterstützt den Nutzen einer aktivierten Klinoptilolith-Suspension als ein Agens zur Erhöhung der Harnausscheidung von toxischen Schwermetallen)
Fassa P, Discover an Effective, Easy, and Inexpensive Heavy Metal Detox Agent, Natural Society, 09. August 2013, (Entdecken Sie ein wirksames, einfaches und kostengünstiges Schwermetall-Ausleitungsagens)
Ortner R, Klinoptilotith-Zeolith, Wigena.de
Adams M, Zeolites contain high levels of lead and aluminum: Health Ranger publishes lab test results after being threatened with legal action by manufacturer, Natural News, (Zeolith enthält hohe Blei- und Aluminiumwerte: Health Ranger veröffentlicht Labortestergebnisse, nachdem ihm von einem Hersteller mit rechtlichen Maßnahmen gedroht wurde.)
Rodgers A, Are All Zeolites Really Toxic?, Touchstone Essentials, (Sind alle Zeolithen giftig?)
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Kein Autor genannt, Clinical evidence activated clinoptilolite suspension removes heavy metals without removing vital electrolytes, Waiora, 2008, (Klinischer Beweis, dass aktivierte Klinoptilotith-Suspension Schwermetalle entfernt, ohne dabei vitale Elektrolyte zu entfernen)
Rodriguez-Fuentes G, et al, Enterex: Anti-diarrheic drug based on purified natural clinoptilolite, Zeolites, November December 1997, (Enterex: Mittel gegen Durchfall basierend auf gereinigten natürlichen Klinoptilotith)
Pavelic K, et al, Natural zeolite clinoptilolite: new adjuvant in anticancer therapy, Journal of Molecular Medicine, 2001;78(12):708-20, (Natürlicher Zeolith Klinoptilotith: neues Adjuvans in der Antikrebstherapie)
Wernert V, et al, Adsorption properties of zeolites for artificial kidney applications, Micoroporous and Mesoporous Materials, 1 September 2005, (Adsorptionsfähigkeit von Zeolithen beim Einsatz künstlicher Nieren)
Pavelic K, et al, Immunostimulatory effect of natural clinoptilolite as a possible mechanism of its antimetastatic ability, Journal of Cancer Research and Clinical Oncology, 2002 Jan;128(1):37-44, (Immunstimulierende Wirkung von natürlichem Klinoptilotith als ein möglicher Mechanismus seiner antimetastatischen Fähigkeit)
Dogliotti G, et al, Natural zeolites chabazite/phillipsite/analcime increase blood levels of antioxidant enzymes, Journal of Clinical Biochemistry and Nutrition, 2012 May; 50(3): 195198
Beltcheva M, et al, Modified natural clinoptilolite detoxifies small mammal's organism loaded with lead I. Lead disposition and kinetic model for lead bioaccumulation., Biological Trace Element Research, 2012 Jun;147(1-3):180-8, (Modifizierter natürlicher Klinoptilolith entgiftet den mit Blei beladenen Organismus des Kleinsäugers.Bleientsorgung und kinetisches Modell für Bleibioakkumulation)
Montinaro M, et al, Dietary zeolite supplementation reduces oxidative damage and plaque generation in the brain of an Alzheimer's disease mouse model, Life Sciences, 2013 May 20;92(17-19):903-10, (Diätische Zeolith-Nahrungsergänzung reduziert oxidative Schäden und Plaquebildung im Hirn von einem Mausmodell mit Alzheimer)
Laurino C, et al, ZEOLITE: "THE MAGIC STONE"; MAIN NUTRITIONAL, ENVIRONMENTAL, EXPERIMENTAL AND CLINICAL FIELDS OF APPLICATION, Nutricion Hospitalaria, 2015 Aug 1;32(2):573-81, (Zeolith: der magische Stein; Haupternährungs, Umgebungs-, experimentielle und klinische Anwendungsfelder)
Gandy JJ, et al, Potentiated clinoptilolite reduces signs and symptoms associated with veisalgia, Clinical and Experimental Gastroenterology, 25 August 2015, (Potenzierter Klinoptilotith reduziert Anzeichen und Symptome, die mit Alkoholintoxikation verbunden sind)
Lamprecht M, et al, Effects of zeolite supplementation on parameters of intestinal barrier integrity, inflammation, redoxbiology and performance in aerobically trained subjects, Journal of the International Society of Sports Nutrition, 2015 Oct 20;12:40, (Wirkung von Zeolith-Nahrungsergänzung auf die Parameter der Darmbarriereintegrität, Entzündung, Redoxbiologie und Leistung bei aerob trainierten Subjekten)
Dr. Karl Hecht, Aluminium, Aluminiumsilikate, Aluminium-Alzheimer-Mythos, OM und Ernährung, 2015
Zitronensaftpulver
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Global 2000, Zitrusfrüchte im Test, November 2016.
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